transforming growth factor beta1

Preferred Label : transforming growth factor beta1;

MeSH definition : A subtype of transforming growth factor beta that is synthesized by a wide variety of cells. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta 1 and TGF-beta1 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor. Defects in the gene that encodes TGF-beta1 are the cause of CAMURATI-ENGELMANN SYNDROME.;

MeSH synonym : tgf-beta1; transforming growth factor beta i; tgf-beta-1; tgf beta 1; Transforming Growth Factor-beta1;

MeSH hyponym : transforming growth factor beta 1 latency associated peptide; TGF-beta1 Latency-Associated Protein; Latency-Associated Protein, TGF-beta1; TGF beta1 Latency Associated Protein; TGF-beta1LAP; TGF beta1LAP;

Is substance : O;

Details

Origin ID

D053773;

UMLS CUI

C1704256;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Recombinant Transforming Growth Factor-Beta 1 [NCIt concept]
- Transforming Growth Factor Beta-1 [NCIt concept]
- Transforming growth factor beta 1 [LOINC component]
- transforming growth factor beta 1 [ORDO Gene]
Indexing information
- N-(3,4-dimethoxyphenethyl)-N-methyl-3-(3-pyridyl)-2-propenamide [MeSH Supplementary Concept]
Record concept(s)
- transforming growth factor beta 1 latency associated peptide [MeSH concept]
- transforming growth factor beta1 [MeSH concept]
Related MeSH Supplementary Concept(s)
- N-FLAG-TGF-beta1 [MeSH Supplementary Concept]
- TGFB1 protein, human [MeSH Supplementary Concept]
- Tgfb1 protein, mouse [MeSH Supplementary Concept]
- Tgfb1 protein, rat [MeSH Supplementary Concept]
- tgfb1a protein, zebrafish [MeSH Supplementary Concept]
- transforming growth factor beta1 (41-65) [MeSH Supplementary Concept]
Related MeSH term(s)
- camurati-engelmann syndrome [MeSH Descriptor]
See also (suggested by CISMeF)
- receptors, transforming growth factor beta [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Transforming growth factor beta 1 [LOINC component]
- Transforming growth factor beta 1 (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

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