apoprotein(a) - CISMeF

Preferred Label : apoprotein(a);

MeSH definition : A large and highly glycosylated protein constituent of LIPOPROTEIN (A). It has very little affinity for lipids but forms disulfide-linkage to APOLIPOPROTEIN B-100. Apoprotein(a) has SERINE PROTEINASE activity and can be of varying sizes from 400- to 800-kDa. It is homologous to PLASMINOGEN and is known to modulate THROMBOSIS and FIBRINOLYSIS.;

MeSH synonym : antiangiogenic ak38 protein; apolipoprotein (a); apolipoprotein lp(a); apolipoprotein lp(a ); apolipoprotein(a); protein, antiangiogenic ak38; Apo Lp(a); apoprotein (a);

Registry Number MeSH : EC 3.4.21.-;

MeSH annotation : do not confuse with APOLIPOPROTEINS A, normal structural proteins of the alpha-lipoproteins (HIGH DENSITY LIPOPROTEINS);

Is substance : O;

Details

Origin ID

D053241;

UMLS CUI

C0085833;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Apolipoprotein [MedDRA Preferred Term]
- Apolipoprotein (substance) [SNOMED CT concept]
- Apolipoprotein A Measurement [NCIt concept]
- Apolipoprotein A-I [MedDRA Preferred Term]
- Apolipoprotein A-I [LOINC component]
- Apolipoprotein A-I (substance) [SNOMED CT concept]
- Apolipoprotein A-I increased [MedDRA Preferred Term]
- Apolipoprotein A-II [MedDRA Preferred Term]
- Apolipoprotein B [LOINC component]
- Apolipoprotein B [MedDRA Preferred Term]
- Apolipoprotein B increased [MedDRA Preferred Term]
- Apolipoprotein C [LOINC component]
- Apolipoprotein C [MedDRA Preferred Term]
- Apolipoprotein C-I [LOINC component]
- Apolipoprotein E [LOINC component]
- Apolipoprotein J (substance) [SNOMED CT concept]
- Apolipoprotein LPA [LOINC component]
- Apolipoprotein LPA (substance) [Inactive SNOMED CT concept]
- Apolipoprotein(a) [OMIM Phenotype]
- Kallikrein-11 [NCIt concept]
- Kallikrein-15 [NCIt concept]
- Lipoprotein [FMA entity]
- Lipoprotein(a) [OMIM gene]
- apolipoprotein a-i [SNOMED Notion]
- apolipoprotein a-ii [SNOMED Notion]
- apolipoprotein b [SNOMED Notion]
- apolipoprotein c [SNOMED Notion]
- apolipoprotein c-i [SNOMED Notion]
- apolipoprotein c-ii [SNOMED Notion]
- apolipoprotein c-iii [SNOMED Notion]
- apolipoprotein d [SNOMED Notion]
- apolipoprotein e [SNOMED Notion]
- apolipoprotein h [SNOMED Notion]
- apolipoprotein lpa [SNOMED Notion]
- apoprotein [IUPAC Term]
- lipid transporter activity [GO term]
- lipoprotein(a) [HGNC gene]
- lipoprotein, nos [SNOMED Notion]
- obsolete apolipoprotein [GO term]
- the a apolipoprotein [medical devices type]
Record concept(s)
- apoprotein(a) [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Apolipoprotein (a) (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

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