gamma catenin - CISMeF

Preferred Label : gamma catenin;

MeSH definition : A multi-functional catenin that is highly homologous to BETA CATENIN. Gamma catenin binds CADHERINS and helps link their cytoplasmic tails to ACTIN in the CYTOSKELETON via ALPHA CATENIN. It is also found in DESMOSOMES where it mediates the link between DESMOSOMAL CADHERINS and DESMOPLAKIN.;

MeSH synonym : plakoglobin; catenin, gamma; gamma-Catenin; Desmoplakin III; Junctional Plakoglobin; Plakoglobin, Junctional; Junction Plakoglobin; Plakoglobin, Junction;

Wikipedia link : https://en.wikipedia.org/wiki/Junction plakoglobin;

Is substance : O;

Details

Origin ID

D051185;

UMLS CUI

C0137209;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- JUP wt Allele [NCIt concept]
- Junction plakoglobin [OMIM gene]
- junction plakoglobin [ORDO Gene]
- junction plakoglobin [HGNC gene]
Currated CISMeF NLP mapping
- Junction Plakoglobin [NCIt concept]
- Plakoglobin [FMA entity]
Record concept(s)
- gamma catenin [MeSH concept]
Related MeSH Supplementary Concept(s)
- JUP protein, human [MeSH Supplementary Concept]
- jup protein, mouse [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Plakoglobin [FMA entity]

Keyword's position in hierarchy(ies) :

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