inhibitor of apoptosis proteins

Preferred Label : inhibitor of apoptosis proteins;

MeSH definition : A conserved class of proteins that control APOPTOSIS in both VERTEBRATES and INVERTEBRATES. IAP proteins interact with and inhibit CASPASES, and they function as ANTI-APOPTOTIC PROTEINS. The protein class is defined by an approximately 80-amino acid motif called the baculoviral inhibitor of apoptosis repeat.; A conserved class of proteins that control APOPTOSIS in both VERTEBRATES and INVERTEBRATES. IAP proteins interact with and inhibit CASPASES, and they function as ANTI-APOPTOTIC PROTEINS. The protein class is defined by an approximately 80-amino acid motif called the baculoviral inhibitor of apoptosis repeat; some members have ubiquitin-protein ligase activity.;

MeSH synonym : inhibitor-of-apoptosis protein; iap protein (apoptosis); apoptosis proteins inhibitor; inhibitor of apoptosis protein; baculoviral inhibitor of apoptosis repeat proteins; IAP Repeat Containing Proteins;

CISMeF synonym : c-IAP2 protein; IAP1 protein;

DeCS synonym : Cellular Inhibitor of Apoptosis 1 Protein; BIRC2 Protein; Baculoviral IAP Repeat-Containing 2 Protein; Baculoviral IAP Repeat Containing Protein 2;

MeSH hyponym : inhibitor of apoptosis 1 protein; inhibitor of apoptosis 2 protein; Baculoviral IAP Repeat Containing 2 Protein; Cellular Inhibitor of Apoptosis 1 Protein; IAP2 Protein; c-IAP1 Protein; cIAP1 Protein; BIRC2 Protein; Baculoviral IAP Repeat Containing Protein 2;

MeSH Related Number : EC 2.3.2.27;

MeSH annotation : APOPTOSIS REGULATORY PROTEINS is also available;

Wikipedia link : https://en.wikipedia.org/wiki/Inhibitor of apoptosis protein;

Is substance : O;

Details

Origin ID

D051034;

UMLS CUI

C0893445;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- IAP Family Protein [NCIt concept]
Indexing information
- 2-(2-(4,4-difluorocyclohexyl)-2-((N-methylalanyl)amino)acetyl)-N-(3,4-dihydro-2H-chromen-4-yl)-7-ethoxyoctahydropyrrolo(1,2-a)pyrazine-3-carboxamide [MeSH Supplementary Concept]
- 6-(2-(methylamino)propanamido)-5-oxo-9-(2-phenylacetamido)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)decahydropyrrolo(1,2-a)azocine-3-carboxamide [MeSH Supplementary Concept]
- DIABLO protein, human [MeSH Supplementary Concept]
- ML183 peptide [MeSH Supplementary Concept]
- N-(5-((2-cyano-1-(2-cyanophenyl)-1H-indol-3-yl)methyl)-4-oxo-2',3',4,5,5',6'-hexahydro-3H-spiro(benzo(b)(1,4)oxazepine-2,4'-pyran)-3-yl)-2-(methylamino)propanamide [MeSH Supplementary Concept]
- N-(5-acetyl-7-cyano-4-methyl-1-((2-methylnaphthalen-1-yl)methyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo(b)(1,4)diazepin-3-yl)-2-(methylamino)propanamide [MeSH Supplementary Concept]
- SH-130 [MeSH Supplementary Concept]
Pharmacological action(s)
- caspase inhibitors [MeSH Descriptor]
Record concept(s)
- Baculoviral IAP Repeat-Containing 2 Protein [MeSH concept]
- inhibitor of apoptosis proteins [MeSH concept]
Related MeSH Supplementary Concept(s)
- BIRC2 protein, human [MeSH Supplementary Concept]
- BIRC3 protein, human [MeSH Supplementary Concept]
- BIRC5 protein, human [MeSH Supplementary Concept]
- BIRC6 protein, human [MeSH Supplementary Concept]
- BIRC6 protein, mouse [MeSH Supplementary Concept]
- BIRC7 protein, human [MeSH Supplementary Concept]
- BIRC8 protein, human [MeSH Supplementary Concept]
- Birc2 protein, mouse [MeSH Supplementary Concept]
- Birc3 protein, mouse [MeSH Supplementary Concept]
- Birc3 protein, rat [MeSH Supplementary Concept]
- Birc4 protein, mouse [MeSH Supplementary Concept]
- Birc5 protein, mouse [MeSH Supplementary Concept]
- Birc5a protein, zebrafish [MeSH Supplementary Concept]
- DIAP1 protein, Drosophila [MeSH Supplementary Concept]
- DIAP2 protein, drosophila [MeSH Supplementary Concept]
- Xiap protein, rat [MeSH Supplementary Concept]
- inhibitor of apoptosis 1 protein, aedes triseriatus [MeSH Supplementary Concept]
- inhibitor of apoptosis, nucleopolyhedrovirus [MeSH Supplementary Concept]
- livin protein, mouse [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- IAP Family Protein [NCIt concept]

Keyword's position in hierarchy(ies) :

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