bcl-2-Associated X protein

Preferred Label : bcl-2-Associated X protein;

MeSH definition : A member of the Bcl-2 protein family and homologous partner of C-BCL-2 PROTO-ONCOGENE PROTEIN. It regulates the release of CYTOCHROME C and APOPTOSIS INDUCING FACTOR from the MITOCHONDRIA. Several isoforms of BCL2-associated X protein occur due to ALTERNATIVE SPLICING of the mRNA for this protein.;

MeSH synonym : bcl2 associated x protein; bcl2-associated x protein; protein, bcl-2-associated x; x protein, bcl-2-associated; bax protein; bax apoptosis regulator protein; bcl 2 associated X protein;

MeSH hyponym : bcl2-Associated X protein isoform sigma; bcl2-Associated X protein isoform omega; bcl2-Associated X protein isoform delta; bcl2-Associated X protein isoform alpha; bcl2-Associated X protein isoform beta; bcl2 Associated X Protein Isoform beta; Bax-beta Protein; Bax beta Protein; bcl2 Associated X Protein Isoform sigma; Bax-sigma Protein; Bax sigma Protein; bcl2 Associated X Protein Isoform omega; Bax-omega Protein; Bax omega Protein; bcl2 Associated X Protein Isoform alpha; Bax-alpha Protein; Bax alpha Protein; bcl2 Associated X Protein Isoform delta; Bax-delta Protein; Bax delta Protein;

MeSH annotation : Don't confuse with the closely related BCL-X PROTEIN;

Wikipedia link : https://en.wikipedia.org/wiki/Bcl-2-associated x protein;

Is substance : O;

Details

Origin ID

D051028;

UMLS CUI

C0219474;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Apoptosis Regulator BAX [NCIt concept]
- BAX Gene [NCIt concept]
- Bcl2-associated X protein [OMIM gene]
Indexing information
- bax-inhibiting peptide, BIP [MeSH Supplementary Concept]
Record concept(s)
- bcl-2-Associated X protein [MeSH concept]
- bcl2-Associated X protein isoform alpha [MeSH concept]
- bcl2-Associated X protein isoform beta [MeSH concept]
- bcl2-Associated X protein isoform delta [MeSH concept]
- bcl2-Associated X protein isoform omega [MeSH concept]
- bcl2-Associated X protein isoform sigma [MeSH concept]
Related MeSH Supplementary Concept(s)
- BAX protein, human [MeSH Supplementary Concept]
- bax protein, mouse [MeSH Supplementary Concept]
- bax protein, rat [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Apoptosis Regulator BAX [NCIt concept]

Keyword's position in hierarchy(ies) :

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