ubiquitin-activating enzymes

Preferred Label : ubiquitin-activating enzymes;

MeSH definition : A class of enzymes that catalyzes the ATP-dependent formation of a thioester bond between itself and UBIQUITIN. It then transfers the activated ubiquitin to one of the UBIQUITIN-PROTEIN LIGASES.;

MeSH synonym : enzyme e1, ubiquitin-activating; ubiquitin activating enzyme; ubiquitin-activating enzyme; enzymes, ubiquitin-activating; ubiquitin-activating enzyme e1; ubiquitin activating enzyme e1; ubiquitination activating enzyme e1; enzyme, ubiquitin-activating; ubiquitin activating enzymes;

MeSH Related Number : EC 6.3.2.19;

Registry Number MeSH : EC 6.3.2.19; EC 6.2.1.45;

Wikipedia link : https://en.wikipedia.org/wiki/Ubiquitin-activating enzyme;

Is substance : O;

UNII : EC 6.2.1.45;

Details

Origin ID

D044764;

UMLS CUI

C0163974;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Indexing information
- Aos1 protein, drosophila [MeSH Supplementary Concept]
Record concept(s)
- Ubiquitin-Activating enzymes [MeSH concept]
Related MeSH Supplementary Concept(s)
- Atg7 protein, human [MeSH Supplementary Concept]
- Atg7 protein, rat [MeSH Supplementary Concept]
- CsdL protein, E coli [MeSH Supplementary Concept]
- E1-L2 protein, mouse [MeSH Supplementary Concept]
- NAE protein, human [MeSH Supplementary Concept]
- Nae1 protein, rat [MeSH Supplementary Concept]
- Nedd8-activating enzyme E1 protein, mouse [MeSH Supplementary Concept]
- RFL-1 protein, C elegans [MeSH Supplementary Concept]
- SAE1 protein, human [MeSH Supplementary Concept]
- SAE1 protein, mouse [MeSH Supplementary Concept]
- UBA1 protein, human [MeSH Supplementary Concept]
- UBA1 protein, rat [MeSH Supplementary Concept]
- UBA2 protein, human [MeSH Supplementary Concept]
- UBA5 protein, human [MeSH Supplementary Concept]
- UBA5 protein, zebrafish [MeSH Supplementary Concept]
- UBA6 protein, human [MeSH Supplementary Concept]
- UBA7 protein, human [MeSH Supplementary Concept]
- Uba1 protein, S cerevisiae [MeSH Supplementary Concept]
- Uba1 protein, drosophila [MeSH Supplementary Concept]
- Uba1 protein, mouse [MeSH Supplementary Concept]
- Uba3 protein, drosophila [MeSH Supplementary Concept]
- Uba5 protein, mouse [MeSH Supplementary Concept]
- Ube1y1 protein, mouse [MeSH Supplementary Concept]
- ptr3 protein, S pombe [MeSH Supplementary Concept]
- uba-5 protein, C elegans [MeSH Supplementary Concept]
- uba2 protein, drosophila [MeSH Supplementary Concept]
- ubiquitin-calmodulin ligase [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- E1 Ubiquitin-Activating Enzyme [NCIt concept]
Validated automatic mappings to BTNT
- Ubiquitin-Activating Enzyme Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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