" /> ubiquitin-protein ligase complexes - CISMeF





Preferred Label : ubiquitin-protein ligase complexes;

MeSH definition : Complexes of enzymes that catalyze the covalent attachment of UBIQUITIN to other proteins by forming a peptide bond between the C-terminal GLYCINE of UBIQUITIN and the alpha-amino groups of LYSINE residues in the protein. The complexes play an important role in mediating the selective-degradation of short-lived and abnormal proteins. The complex of enzymes can be broken down into three components that involve activation of ubiquitin (UBIQUITIN-ACTIVATING ENZYMES), conjugation of ubiquitin to the ligase complex (UBIQUITIN-CONJUGATING ENZYMES), and ligation of ubiquitin to the substrate protein (UBIQUITIN-PROTEIN LIGASES).;

MeSH synonym : ligase complexes, ubiquitin-protein; complexes, ubiquitin-protein ligase; ubiquitin protein ligase complexes;

MeSH Related Number : EC 2.3.2.26; EC 2.3.2.27; EC 6.2.1.45;

Registry Number MeSH : EC 6.3.2.19; EC 2.3.2.23;

MeSH annotation : UBIQUITIN-PROTEIN LIGASES is also available;

Is substance : O;

UNII : EC 2.3.2.23;

Details


Keyword's position in hierarchy(ies) : arborescence

You can consult :

Complexes of enzymes that catalyze the covalent attachment of UBIQUITIN to other proteins by forming a peptide bond between the C-terminal GLYCINE of UBIQUITIN and the alpha-amino groups of LYSINE residues in the protein. The complexes play an important role in mediating the selective-degradation of short-lived and abnormal proteins. The complex of enzymes can be broken down into three components that involve activation of ubiquitin (UBIQUITIN-ACTIVATING ENZYMES), conjugation of ubiquitin to the ligase complex (UBIQUITIN-CONJUGATING ENZYMES), and ligation of ubiquitin to the substrate protein (UBIQUITIN-PROTEIN LIGASES).

Nous contacter.
19/05/2024


[Home] [Top]

© Rouen University Hospital. Any partial or total use of this material must mention the source.