glutamate carboxypeptidase ii

Preferred Label : glutamate carboxypeptidase ii;

MeSH definition : A metallocarboxypeptidase that is predominantly expressed as a membrane-bound enzyme. It catalyzes the hydrolysis of an unsubstituted, C-terminal glutamyl residue, typically from PTEROYLPOLYGLUTAMIC ACIDS. It was formerly classified as EC 3.4.19.8.;

MeSH synonym : acidic dipeptidase, n-acetylated-alpha-linked; folh1 protein; hydrolase i, folate; n acetylated alpha linked acidic dipeptidase; naag peptidase; naaladase; naaladase l; n-acetylaspartylglutamate peptidase; peptidase, n-acetylaspartylglutamate; carboxypeptidase ii, glutamate; n acetylaspartylglutamate peptidase; naaladase ii; folate hydrolase i; n-acetylated-alpha-linked acidic dipeptidase; dipeptidase, n-acetylated-alpha-linked acidic;

Registry Number MeSH : EC 3.4.17.21;

Wikipedia link : https://en.wikipedia.org/wiki/Glutamate carboxypeptidase ii;

Is substance : O;

UNII : EC 3.4.17.21;

Details

Origin ID

D043425;

UMLS CUI

C0067685;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- FOLH1 wt Allele [NCIt concept]
- Folate hydrolase 1 [OMIM gene]
- Glutamate carboxypeptidase (substance) [SNOMED CT concept]
- Glutamate carboxypeptidase II (substance) [SNOMED CT concept]
- N-acetylated alpha-linked acidic dipeptidase 2 [OMIM gene]
- N-acetylated alpha-linked acidic dipeptidase-like 1 [OMIM gene]
Currated CISMeF NLP mapping
- Glutamate Carboxypeptidase 2 [NCIt concept]
Indexing information
- 2-(3-(1-carboxy-2-(4-hydroxyphenyl)ethyl)ureido)pentanedioic acid [MeSH Supplementary Concept]
- 2-(hydroxypentafluorophenylmethylphosphinoylmethyl)pentanedioic acid [MeSH Supplementary Concept]
- 3-((1-carboxy-4-mercaptobutyl)thio)benzoic acid [MeSH Supplementary Concept]
- 3-(1-carboxy-4-mercaptobutoxy)benzoic acid [MeSH Supplementary Concept]
Record concept(s)
- glutamate carboxypeptidase II [MeSH concept]
Related MeSH Supplementary Concept(s)
- FOLH1 protein, human [MeSH Supplementary Concept]
- Folh1 protein, mouse [MeSH Supplementary Concept]
- NAALADL2 protein, human [MeSH Supplementary Concept]
- PSMA protein, mouse [MeSH Supplementary Concept]
- glutamate carboxypeptidase III, mouse [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Glutamate carboxypeptidase II (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

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