phosphodiesterase i

Preferred Label : phosphodiesterase i;

MeSH definition : A phosphoric diester hydrolase that removes 5'-nucleotides from the 3'-hydroxy termini of 3'-hydroxy-terminated OLIGONUCLEOTIDES. It has low activity towards POLYNUCLEOTIDES and the presence of 3'-phosphate terminus on the substrate may inhibit hydrolysis.;

MeSH synonym : alkaline phosphodiesterase; alkaline phosphodiesterase i; diester phosphohydrolase, orthophosphoric; oligonucleate 5' nucleotidohydrolase; oligonucleate 5'-nucleotidohydrolase; orthophosphoric diester phosphohydrolase; phosphodiesterase, alkaline; phosphodiesterase i, alkaline; phosphohydrolase, orthophosphoric diester; 5' exonuclease; 5' nucleotidephosphodiesterase; 5'-exonuclease; 5'-nucleotidephosphodiesterase;

MeSH Related Number : 9025-82-5 (CRN);

Registry Number MeSH : EC 3.1.4.1;

Is substance : O;

UNII : EC 3.1.4.1;

Details

Origin ID

D043264;

UMLS CUI

C0070828;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- 3'-5' Exonuclease [NCIt concept]
- 5'-3' Exonuclease [NCIt concept]
- Ectonucleotide pyrophosphatase/phosphodiesterase 1 [OMIM gene]
- Exonuclease [NCIt concept]
- Exonuclease 5 [OMIM gene]
- Phosphodiesterase I (substance) [SNOMED CT concept]
- Phospholipase A2 Enzyme Family [NCIt concept]
- Spleen exonuclease (substance) [SNOMED CT concept]
- exonuclease 5 [HGNC gene]
- phosphodiesterase i [SNOMED Notion]
- phosphoric diester hydrolase activity [GO term]
- spleen exonuclease [SNOMED Notion]
Indexing information
- KF 19514 [MeSH Supplementary Concept]
- scolochinenoside C [MeSH Supplementary Concept]
Record concept(s)
- phosphodiesterase I [MeSH concept]
Related MeSH Supplementary Concept(s)
- phosphodiesterase I, snake venom [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Phosphodiesterase I (substance) [SNOMED CT concept]
- phosphodiesterase i [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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