" /> Bryostatin 1 - CISMeF





Preferred Label : Bryostatin 1;

NCIt synonyms : Bryostatin-1;

NCIt related terms : Bryostatin I; B705008K112;

NCIt definition : A macrocyclic lactone isolated from the bryozoan Bugula neritina with antineoplastic activity. Bryostatin 1 binds to and inhibits the cell-signaling enzyme protein kinase C, resulting in the inhibition of tumor cell proliferation, the promotion of tumor cell differentiation, and the induction of tumor cell apoptosis. This agent may act synergistically with other chemotherapeutic agents. (NCI04);

Alternative definition : NCI-GLOSS: A substance being studied in the treatment of cancer and certain brain conditions such as Alzheimer disease and stroke. It binds to an enzyme involved in cell growth and it may help anticancer drugs work better. Bryostatin 1 comes from a marine organism. It is a type of protein kinase C modulator.;

UNII : 37O2X55Y9E;

InChIKey : MJQUEDHRCUIRLF-TVIXENOKSA-N;

CAS number : 83314-01-6; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 83314-01-6 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : B705008K112;

Chemical formula : C47H68O17;

NSC code : 339555;

Codes from synonyms : 01979; NSC0339555; CDR0000045630;

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15/05/2024


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