polypyrimidine Tract-Binding protein

Preferred Label : polypyrimidine Tract-Binding protein;

MeSH definition : A RNA-binding protein that binds to polypyriminidine rich regions in the INTRONS of messenger RNAs. Polypyrimidine tract-binding protein may be involved in regulating the ALTERNATIVE SPLICING of mRNAs since its presence on an intronic RNA region that is upstream of an EXON inhibits the splicing of the exon into the final mRNA product.;

MeSH synonym : pptb; ptb splicing factor; p57 cytoplasmic rna-binding protein; tract-binding protein, polypyrimidine; splicing factor, ptb; ptb protein; p57 cytoplasmic rna binding protein; polypyrimidine tract binding protein;

Registry Number MeSH : 139076-35-0;

Is substance : O;

Details

Origin ID

D038941;

UMLS CUI

C0137872;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Record concept(s)
- polypyrimidine Tract-Binding protein [MeSH concept]
Related MeSH Supplementary Concept(s)
- Heph protein, Drosophila [MeSH Supplementary Concept]
- PTBP1 protein, human [MeSH Supplementary Concept]
- PTBP2 protein, human [MeSH Supplementary Concept]
- PTBP2 protein, rat [MeSH Supplementary Concept]
- PTBP3 protein, human [MeSH Supplementary Concept]
- Ptbp1 protein, mouse [MeSH Supplementary Concept]
- Ptbp1 protein, rat [MeSH Supplementary Concept]
- Ptbp2 protein, mouse [MeSH Supplementary Concept]
- hnRNP I-related RNA transport protein VgRBP60, xenopus [MeSH Supplementary Concept]
- polypyrimidine tract binding protein 1, Xenopus [MeSH Supplementary Concept]
See also
- PTB-Associated Splicing Factor [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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