PTB-Associated Splicing Factor

Preferred Label : PTB-Associated Splicing Factor;

MeSH definition : An RNA splicing factor that also binds DNA. It is essential for pre-mRNA spicing in the formation of early SPLICEOSOMES and catalytic step II. It binds specifically to polypyrimidine tracts in INTRONS and is involved in the regulation of ALTERNATIVE SPLICING by SIGNAL TRANSDUCTION PATHWAYS.;

MeSH synonym : PTB Associated Splicing Factor; Splicing Factor, PTB-Associated; Splicing Factor Proline-Glutamine Rich Protein; Splicing Factor Proline Glutamine Rich Protein; Polypyrimidine Tract-Binding Protein-Associated Splicing Factor; Polypyrimidine Tract Binding Protein Associated Splicing Factor; PSF Splicing Factor; Splicing Factor, PSF; SFPQ Protein;

Details

Origin ID

D000072670;

UMLS CUI

C0214345;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Splicing Factor Proline-and Glutamine-Rich [NCIt concept]
- Splicing factor, proline- and glutamine-rich [OMIM gene]
Record concept(s)
- PTB-associated splicing factor [MeSH concept]
See also
- polypyrimidine Tract-Binding protein [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Splicing Factor Proline-and Glutamine-Rich [NCIt concept]

Keyword's position in hierarchy(ies) :

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