silent information regulator proteins, saccharomyces cerevisiae

Preferred Label : silent information regulator proteins, saccharomyces cerevisiae;

MeSH definition : A set of nuclear proteins in SACCHAROMYCES CEREVISIAE that are required for the transcriptional repression of the silent mating type loci. They mediate the formation of silenced CHROMATIN and repress both transcription and recombination at other loci as well. They are comprised of 4 non-homologous, interacting proteins, Sir1p, Sir2p, Sir3p, and Sir4p. Sir2p, an NAD-dependent HISTONE DEACETYLASE, is the founding member of the family of SIRTUINS.;

MeSH synonym : silent information regulator proteins, s cerevisiae; sir proteins, s cerevisiae;

MeSH hyponym : silent mating type information regulator protein, S cerevisiae;

Wikipedia link : https://en.wikipedia.org/wiki/Silent information regulator proteins, saccharomyces cerevisiae;

Is substance : O;

Details

Origin ID

D038281;

UMLS CUI

C1136204;

Allowable qualifiers
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Record concept(s)
- silent information regulator proteins, saccharomyces cerevisiae [MeSH concept]
- silent mating type information regulator protein, S cerevisiae [MeSH concept]
Related MeSH Supplementary Concept(s)
- SIR1 protein, S cerevisiae [MeSH Supplementary Concept]
- SIR2 protein, S cerevisiae [MeSH Supplementary Concept]
- SIR3 protein, S cerevisiae [MeSH Supplementary Concept]
- SIR4 protein, S cerevisiae [MeSH Supplementary Concept]
See also
- sirtuins [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

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