calreticulin - CISMeF

Preferred Label : calreticulin;

MeSH definition : A multifunctional protein that is found primarily within membrane-bound organelles. In the ENDOPLASMIC RETICULUM it binds to specific N-linked oligosaccharides found on newly-synthesized proteins and functions as a MOLECULAR CHAPERONE that may play a role in PROTEIN FOLDING or retention and degradation of misfolded proteins. In addition calreticulin is a major storage form for CALCIUM and functions as a calcium-signaling molecule that can regulate intracellular calcium HOMEOSTASIS.;

MeSH synonym : cab-63; calcium-binding protein-3; cbp3 (liver); erp60; hacbp; 55-kda high-affinity calcium binding protein; 55 kda high affinity calcium binding protein; calcium binding protein 3; calregulin; cc1qr protein;

Wikipedia link : https://en.wikipedia.org/wiki/Calreticulin;

Is substance : O;

Details

Origin ID

D037282;

UMLS CUI

C0054543;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Calreticulin [NCIt concept]
Record concept(s)
- calreticulin [MeSH concept]
Related MeSH Supplementary Concept(s)
- AT1G09210 protein, Arabidopsis [MeSH Supplementary Concept]
- AT1G56340 protein, Arabidopsis [MeSH Supplementary Concept]
- CALR protein, human [MeSH Supplementary Concept]
- CRT-1 protein, C elegans [MeSH Supplementary Concept]
- RAL-1 protein, schistosoma japonicum [MeSH Supplementary Concept]
- calreticulin 3, arabidopsis [MeSH Supplementary Concept]
- vasostatin [MeSH Supplementary Concept]
- vasostatin 48 [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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