Preferred Label : rna interference;
MeSH definition : A gene silencing phenomenon whereby specific dsRNAs (RNA, DOUBLE-STRANDED) trigger
the degradation of homologous mRNA (RNA, MESSENGER). The specific dsRNAs are processed
into SMALL INTERFERING RNA (siRNA) which serves as a guide for cleavage of the homologous
mRNA in the RNA-INDUCED SILENCING COMPLEX. DNA METHYLATION may also be triggered during
this process.;
MeSH synonym : gene silencing, post transcriptional; gene silencing, posttranscriptional; post transcriptional gene silencing; silencing, post-transcriptional gene; interference, rna; gene silencing, post-transcriptional; post-transcriptional gene silencings; post-transcriptional gene silencing; posttranscriptional gene silencing; gene silencings, posttranscriptional; RNA silencing; RNAi;
Related MeSH term : cosuppression; Co-Suppression; Co Suppression;
Wikipedia link : https://en.wikipedia.org/wiki/Post-transcriptional gene silencing;
Origin ID : D034622;
UMLS CUI : C1136031;
Allowable qualifiers
- Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- Indexing information
- Record concept(s)
- See also
- Semantic type(s)
- UMLS correspondences (same concept)
A gene silencing phenomenon whereby specific dsRNAs (RNA, DOUBLE-STRANDED) trigger
the degradation of homologous mRNA (RNA, MESSENGER). The specific dsRNAs are processed
into SMALL INTERFERING RNA (siRNA) which serves as a guide for cleavage of the homologous
mRNA in the RNA-INDUCED SILENCING COMPLEX. DNA METHYLATION may also be triggered during
this process.
