ubiquitin - CISMeF

Preferred Label : ubiquitin;

MeSH definition : A highly conserved 76-amino acid peptide universally found in eukaryotic cells that functions as a marker for intracellular PROTEIN TRANSPORT and degradation. Ubiquitin becomes activated through a series of complicated steps and forms an isopeptide bond to lysine residues of specific proteins within the cell. These ubiquitinated proteins can be recognized and degraded by proteosomes or be transported to specific compartments within the cell.;

MeSH synonym : atp-dependent proteolysis factor 1; high mobility protein 20; hmg-20; apf-1; atp dependent proteolysis factor 1;

MeSH hyponym : ubiquitin, human; Human Ubiquitin;

MeSH Related Number : ubiquitin, human; 79586-22-4 (human);

Related CAS MeSH : 79586-22-4 (Ubiquitin, human);

MeSH annotation : UBIQUITINS is also available;

Wikipedia link : https://en.wikipedia.org/wiki/Ubiquitin;

Is substance : O;

Details

Origin ID

D025801;

UMLS CUI

C0041538;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- UBC wt Allele [NCIt concept]
- Ubiquitin [LOINC component]
- Ubiquitination [NCIt concept]
- obsolete ubiquitin [GO term]
- protein tag [GO term]
Currated CISMeF NLP mapping
- Ubiquitin [NCIt concept]
- Ubiquitin (substance) [SNOMED CT concept]
- ubiquitin [SNOMED Notion]
Indexing information
- COP10 protein, arabidopsis [MeSH Supplementary Concept]
- UBAP1 protein, human [MeSH Supplementary Concept]
- UBR5 protein, human [MeSH Supplementary Concept]
Record concept(s)
- ubiquitin [MeSH concept]
- ubiquitin, human [MeSH concept]
Related MeSH Supplementary Concept(s)
- Mdy2 protein, S cerevisiae [MeSH Supplementary Concept]
- UBB protein, human [MeSH Supplementary Concept]
- amniotic fluid peptide-1, human [MeSH Supplementary Concept]
- arthrin [MeSH Supplementary Concept]
- ubb protein, mouse [MeSH Supplementary Concept]
- ubiquitin 50-59, human [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Ubiquitin [LOINC component]
- Ubiquitin [NCIt concept]
- Ubiquitin (substance) [SNOMED CT concept]
- ubiquitin [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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