BRCA2 protein - CISMeF

Preferred Label : BRCA2 protein;

MeSH definition : A large, nuclear protein, encoded by the BRCA2 gene (GENE, BRCA2). Mutations in this gene predispose humans to breast and ovarian cancer. The BRCA2 protein is an essential component of DNA repair pathways, suppressing the formation of gross chromosomal rearrangements. (from Genes Dev. 2000;14(11):1400-6);

MeSH synonym : fanconi anemia group d1 protein; breast cancer 2 gene product; fanconi anemia complementation group d1 protein; breast cancer 2 protein; fanconi anemia group d1 complementing protein; brca2 gene product; fancd1 protein;

Is substance : O;

Details

Origin ID

D024682;

UMLS CUI

C0294028;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Record concept(s)
- BRCA2 protein [MeSH concept]
Related MeSH Supplementary Concept(s)
- BRCA2 protein, chicken [MeSH Supplementary Concept]
- BRCA2 protein, human [MeSH Supplementary Concept]
- BRCA2 protein, mouse [MeSH Supplementary Concept]
- brca2 protein, zebrafish [MeSH Supplementary Concept]
See also
- genes, BRCA2 [MeSH Descriptor]
- hereditary breast and ovarian cancer syndrome [MeSH Descriptor]
See also (suggested by CISMeF)
- breast neoplasms [MeSH Descriptor]
- ovarian neoplasms [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Breast cancer type 2 susceptibility protein (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

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