genes, BRCA2 - CISMeF

Preferred Label : genes, BRCA2;

MeSH definition : A tumor suppressor gene (GENES, TUMOR SUPPRESSOR) located on human chromosome 13 at locus 13q12.3. Mutations in this gene predispose humans to breast and ovarian cancer. It encodes a large, nuclear protein that is an essential component of DNA repair pathways, suppressing the formation of gross chromosomal rearrangements. (from Genes Dev 2000;14(11):1400-6);

MeSH synonym : brca2 genes; gene, brca2; brca2 gene;

CISMeF synonym : BRCA2;

MeSH annotation : BRCA stands for BReast CAncer;

Wikipedia link : https://en.wikipedia.org/wiki/Genes, brca2;

Details

Origin ID

D024522;

UMLS CUI

C0598034;

Allowable qualifiers
- drug effects [MeSH Qualifier]
- ethics [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- BRCA2 [LOINC component]
- BRCA2 DNA repair associated [ORDO Gene]
- BRCA2 gene [LOINC component]
- Brca2 dna repair-associated protein [OMIM gene]
- Breast Cancer Type 2 Susceptibility Protein [NCIt concept]
Currated CISMeF NLP mapping
- BRCA2 Gene [NCIt concept]
Record concept(s)
- genes, BRCA2 [MeSH concept]
See also
- BRCA2 protein [MeSH Descriptor]
See also (suggested by CISMeF)
- breast neoplasms [MeSH Descriptor]
- ovarian neoplasms [MeSH Descriptor]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
UMLS correspondences (same concept)
- BRCA2 [LOINC component]
- BRCA2 DNA repair associated [HGNC gene]
- BRCA2 Gene [NCIt concept]
- BRCA2 gene [LOINC component]
- Brca2 dna repair-associated protein [OMIM gene]

Keyword's position in hierarchy(ies) :

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