cd40 ligand - CISMeF

Preferred Label : cd40 ligand;

MeSH definition : A membrane glycoprotein and differentiation antigen expressed on the surface of T-cells that binds to CD40 ANTIGENS on B-LYMPHOCYTES and induces their proliferation. Mutation of the gene for CD40 ligand is a cause of HYPER-IGM IMMUNODEFICIENCY SYNDROME, TYPE 1.;

MeSH synonym : antigen, cd154; antigens, cd154; cd154 antigen; cd154 antigens; cd40l; gp39 antigen, t cell; gp39 antigen, t-cell; t-b cell activating molecule; t-cell gp39 antigen; tnf superfamily, member 5; tumor necrosis factor ligand superfamily member 5;

Registry Number MeSH : 147205-72-9;

Is substance : O;

Details

Origin ID

D023201;

UMLS CUI

C0167627;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- CD40 Ligand [NCIt concept]
Indexing information
- 2-(2'-(biphenyl-3-ylmethylcarbamoyl)-6,6'-bis(2-(pyrrolidin-1-ylmethyl)pyrrolidine-1-carbonyl)-4,4'-bipyridine-2-carboxamido)-2-cyclohexylacetic acid [MeSH Supplementary Concept]
Record concept(s)
- CD40 ligand [MeSH concept]
Related MeSH Supplementary Concept(s)
- ABI793 monoclonal antibody [MeSH Supplementary Concept]
See also
- CD40 Antigens [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- CD154 [LOINC component]
- Lymphocyte antigen CD154 (substance) [SNOMED CT concept]
- trapping [IUPAC Term]

Keyword's position in hierarchy(ies) :

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