Preferred Label : antimicrobial cationic peptides;
MeSH definition : Small cationic peptides that are an important component, in most species, of early
innate and induced defenses against invading microbes. In animals they are found on
mucosal surfaces, within phagocytic granules, and on the surface of the body. They
are also found in insects and plants. Among others, this group includes the DEFENSINS,
protegrins, tachyplesins, and thionins. They displace DIVALENT CATIONS from phosphate
groups of MEMBRANE LIPIDS leading to disruption of the membrane.;
MeSH synonym : peptides, cationic antimicrobial; peptides, antimicrobial cationic; microbicidal cationic proteins; cationic peptides, antimicrobial; cationic proteins, microbicidal; proteins, microbicidal cationic; cationic antimicrobial peptides; antimicrobial peptides, cationic; Cationic Host Defense Peptides; Cationic Antimicrobial Peptide; Antimicrobial Peptide, Cationic; Peptide, Cationic Antimicrobial;
CISMeF synonym : Host Defense Peptides;
MeSH hyponym : amphipathic cationic antimicrobial peptides;
Related MeSH term : Defense Peptides, Host; Peptides, Host Defense; Host Defense Peptide; Defense Peptide, Host; Peptide, Host Defense;
Is substance : O;
Origin ID : D023181;
UMLS CUI : C0066510;
Allowable qualifiers
Automatic exact mappings (from CISMeF team)
Indexing information
Pharmacological action(s)
Record concept(s)
Related MeSH Supplementary Concept(s)
- A 10947 [MeSH Supplementary Concept]
- AMP2041 [MeSH Supplementary Concept]
- AN 3 [MeSH Supplementary Concept]
- AP138 [MeSH Supplementary Concept]
- ASK 753 [MeSH Supplementary Concept]
- B 43 [MeSH Supplementary Concept]
- BMAP-27 [MeSH Supplementary Concept]
- BPC194 [MeSH Supplementary Concept]
- D2A21 [MeSH Supplementary Concept]
- FALL 39 [MeSH Supplementary Concept]
- GRN-41 [MeSH Supplementary Concept]
- K 582 A [MeSH Supplementary Concept]
- KM 8 [MeSH Supplementary Concept]
- LLKKK18 [MeSH Supplementary Concept]
- M-81 [MeSH Supplementary Concept]
- MSI 511 [MeSH Supplementary Concept]
- NZ17074 [MeSH Supplementary Concept]
- PMAP-36 [MeSH Supplementary Concept]
- PMAP-37 [MeSH Supplementary Concept]
- PR 26 [MeSH Supplementary Concept]
- PR 39 [MeSH Supplementary Concept]
- SB 37 [MeSH Supplementary Concept]
- SPR741 [MeSH Supplementary Concept]
- SR-0379 [MeSH Supplementary Concept]
- Shiva-1 [MeSH Supplementary Concept]
- XK-19-2 [MeSH Supplementary Concept]
- XR 586 [MeSH Supplementary Concept]
- anoplin [MeSH Supplementary Concept]
- antapin [MeSH Supplementary Concept]
- bresein [MeSH Supplementary Concept]
- crustin [MeSH Supplementary Concept]
- esein [MeSH Supplementary Concept]
- gomesin [MeSH Supplementary Concept]
- hevein [MeSH Supplementary Concept]
- myticin [MeSH Supplementary Concept]
- mytilin [MeSH Supplementary Concept]
- omega76 [MeSH Supplementary Concept]
- oncocin [MeSH Supplementary Concept]
- shiva 3 [MeSH Supplementary Concept]
See also
Semantic type(s)
Small cationic peptides that are an important component, in most species, of early
innate and induced defenses against invading microbes. In animals they are found on
mucosal surfaces, within phagocytic granules, and on the surface of the body. They
are also found in insects and plants. Among others, this group includes the DEFENSINS,
protegrins, tachyplesins, and thionins. They displace DIVALENT CATIONS from phosphate
groups of MEMBRANE LIPIDS leading to disruption of the membrane.