vigabatrin - CISMeF

Preferred Label : vigabatrin;

MeSH definition : An analogue of GAMMA-AMINOBUTYRIC ACID. It is an irreversible inhibitor of 4-AMINOBUTYRATE TRANSAMINASE, the enzyme responsible for the catabolism of GAMMA-AMINOBUTYRIC ACID. (From Martindale The Extra Pharmacopoeia, 31st ed); An analogue of GAMMA-AMINOBUTYRIC ACID. It is an irreversible inhibitor of 4-AMINOBUTYRATE TRANSAMINASE, the enzyme responsible for the catabolism of GAMMA-AMINOBUTYRIC ACID and is used as an anticonvulsant. (From Martindale The Extra Pharmacopoeia, 31st ed);

MeSH synonym : gamma vinyl gamma aminobutyric acid; gamma-vinyl-gamma-aminobutyric acid; gamma vinyl gaba; gamma-vinyl-gaba;

CISMeF synonym : yamanouchi brand of vigabatrin; vigabatrin yamanouchi brand; aventis brand of vigabatrin; vigabatrin aventis brand; hoechst brand of vigabatrin; vigabatrin hoechst brand; acid, gamma-vinyl-gamma-aminobutyric; sabrilex;

MeSH hyponym : sabril;

MeSH CAS label : 4-Amino-5-hexenoic acid;

MeSH Related Number : 60643-86-9 (Vigabatrin);

Registry Number MeSH : 60643-86-9;

Wikipedia link : https://en.wikipedia.org/wiki/Vigabatrin;

Is substance : O;

UNII : GR120KRT6K;

InChIKey : PJDFLNIOAUIZSL-UHFFFAOYSA-N;

Details

Origin ID

D020888;

UMLS CUI

C0048044;

ATC code(s)
- vigabatrin [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
CISMeF manual mappings
- Vigabatrin poisoning (disorder) [SNOMED CT concept]
Pharmacological action(s)
- GABA agents [MeSH Descriptor]
- anticonvulsants [MeSH Descriptor]
- enzyme inhibitors [MeSH Descriptor]
Record concept(s)
- Sabrilex [MeSH concept]
- sabril [MeSH concept]
- vigabatrin [MeSH concept]
See also inter- (CISMeF)
- Product containing vigabatrin (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing vigabatrin (medicinal product) [SNOMED CT concept]
- Vigabatrin [ICD-11 Extension code]
- Vigabatrin [NCIt concept]
- Vigabatrin [LOINC component]
- Vigabatrin (substance) [SNOMED CT concept]
- vigabatrin [ATC Code]
Validated automatic mappings to BTNT
- vigabatrin [ATC Code]

Keyword's position in hierarchy(ies) :

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