MeSH definition : The Alu sequence family (named for the restriction endonuclease cleavage enzyme Alu
I) is the most highly repeated interspersed repeat element in humans (over a million
copies). It is derived from the 7SL RNA component of the SIGNAL RECOGNITION PARTICLE
and contains an RNA polymerase III promoter. Transposition of this element into coding
and regulatory regions of genes is responsible for many heritable diseases.;
MeSH synonym : alu element; alu family; alu repetitive sequence; family, alu; sequence, alu repetitive; element, alu; elements, alu; alu families; families, alu; alu repetitive sequences; repetitive sequence, alu; repetitive sequences, alu; sequences, alu repetitive;
Related MeSH term : Alu-Like repetitive sequence;
Wikipedia link : https://en.wikipedia.org/wiki/Alu element;
The Alu sequence family (named for the restriction endonuclease cleavage enzyme Alu
I) is the most highly repeated interspersed repeat element in humans (over a million
copies). It is derived from the 7SL RNA component of the SIGNAL RECOGNITION PARTICLE
and contains an RNA polymerase III promoter. Transposition of this element into coding
and regulatory regions of genes is responsible for many heritable diseases.