mutagenesis, insertional

Preferred Label : mutagenesis, insertional;

MeSH definition : Mutagenesis where the mutation is caused by the introduction of foreign DNA sequences into a gene or extragenic sequence. This may occur spontaneously in vivo or be experimentally induced in vivo or in vitro. Proviral DNA insertions into or adjacent to a cellular proto-oncogene can interrupt GENETIC TRANSLATION of the coding sequences or interfere with recognition of regulatory elements and cause unregulated expression of the proto-oncogene resulting in tumor formation.;

MeSH synonym : insertional mutagenesis;

MeSH Hyperonym : insertional activation; Activation, Insertional; Activations, Insertional; Insertional Activations;

MeSH hyponym : Linker-Insertion mutagenesis; mutagenesis, cassette; viral insertional mutagenesis; Insertional Mutagenesis, Viral; Mutagenesis, Viral Insertional; Linker Insertion Mutagenesis; Mutagenesis, Linker-Insertion; Cassette Mutagenesis;

Related MeSH term : sequence insertion; insertion mutation; gene insertion; Insertion, Sequence; Insertions, Sequence; Sequence Insertions; Gene Insertions; Insertion, Gene; Insertions, Gene; Insertion Mutations; Mutation, Insertion; Mutations, Insertion;

Wikipedia link : https://en.wikipedia.org/wiki/Insertional mutagenesis;

Details

Origin ID

D016254;

UMLS CUI

C0079868;

Allowable qualifiers
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- instrumentation [MeSH Qualifier]
- methods [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- statistics and numerical data [MeSH Qualifier]
Currated CISMeF NLP mapping
- Insertional Mutagenesis [NCIt concept]
Record concept(s)
- Linker-Insertion mutagenesis [MeSH concept]
- gene insertion [MeSH concept]
- insertion mutation [MeSH concept]
- insertional activation [MeSH concept]
- mutagenesis, cassette [MeSH concept]
- mutagenesis, insertional [MeSH concept]
- sequence insertion [MeSH concept]
- viral insertional mutagenesis [MeSH concept]
See also
- DNA transposable elements [MeSH Descriptor]
- alu elements [MeSH Descriptor]
- interspersed repetitive sequences [MeSH Descriptor]
- proviruses [MeSH Descriptor]
- retroelements [MeSH Descriptor]
Semantic type(s)
- Genetic Function [UMLS semantic type]
UMLS correspondences (same concept)
- Insertional Mutagenesis [NCIt concept]

Keyword's position in hierarchy(ies) :

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