Cyclin-Dependent kinase inhibitor p16

Preferred Label : Cyclin-Dependent kinase inhibitor p16;

MeSH definition : A product of the p16 tumor suppressor gene (GENES, P16). It is also called INK4 or INK4A because it is the prototype member of the INK4 CYCLIN-DEPENDENT KINASE INHIBITORS. This protein is produced from the alpha mRNA transcript of the p16 gene. The other gene product, produced from the alternatively spliced beta transcript, is TUMOR SUPPRESSOR PROTEIN P14ARF. Both p16 gene products have tumor suppressor functions.;

MeSH synonym : cdkn2a protein; cdk4 associated protein p16; cyclin dependent kinase inhibitor 2a; ink4a protein; mts1 protein; multiple tumor suppressor 1; cdkn2 protein; cyclin-dependent kinase inhibitor-2a; p16ink4a protein; multiple tumor suppressor-1; p16(ink4a); p16ink4 protein; cdk4-associated protein p16; protein, ink4a; cyclin dependent kinase inhibitor p16;

Is substance : O;

Details

Origin ID

D019941;

UMLS CUI

C0249880;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Cyclin-Dependent Kinase Inhibitor 2A [NCIt concept]
Record concept(s)
- Cyclin-Dependent kinase inhibitor p16 [MeSH concept]
Related MeSH Supplementary Concept(s)
- CDKN2A protein, human [MeSH Supplementary Concept]
- Cdkn2a protein, mouse [MeSH Supplementary Concept]
- p12(INK4a) protein, human [MeSH Supplementary Concept]
See also
- genes, p16 [MeSH Descriptor]
- tumor suppressor protein p14arf [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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