losartan - CISMeF

Preferred Label : losartan;

MeSH definition : An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.;

MeSH synonym : 2-butyl-4-chloro-1-((2'-(1h-etrazol-5-yl) (1,1'-biphenyl)-4-yl)methyl)-1h-imidazole-5-methanol;

CISMeF synonym : 124750-99-8 (Losartan potassium);

MeSH hyponym : MK-954; DuP-753; losartan potassium; cozaar; DuP 753; DuP753; MK 954; MK954; Potassium, Losartan; Losartan Monopotassium Salt; Monopotassium Salt, Losartan; Salt, Losartan Monopotassium;

MeSH Related Number : losartan potassium; 114798-26-4 (Losartan); 124750-99-8 (mono-K salt); 3ST302B24A;

Registry Number MeSH : 114798-26-4;

Related CAS MeSH : 3ST302B24A (Losartan potassium);

Wikipedia link : https://en.wikipedia.org/wiki/Losartan;

Is substance : O;

UNII : JMS50MPO89;

InChIKey : PSIFNNKUMBGKDQ-UHFFFAOYSA-N;

Details

Origin ID

D019808;

UMLS CUI

C0126174;

ATC code(s)
- losartan [ATC Code]
- losartan and amlodipine [ATC Code]
- losartan and diuretics [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
CISMeF manual mappings
- Adverse reaction caused by losartan (disorder) [SNOMED CT concept]
Currated CISMeF NLP mapping
- Losartan [LOINC component]
- Losartan [NCIt concept]
- Losartan (substance) [SNOMED CT concept]
- losartan [SNOMED Notion]
Pharmacological action(s)
- angiotensin II type 1 receptor blockers [MeSH Descriptor]
- anti-arrhythmia agents [MeSH Descriptor]
- antihypertensive agents [MeSH Descriptor]
Record concept(s)
- DuP-753 [MeSH concept]
- MK-954 [MeSH concept]
- cozaar [MeSH concept]
- losartan [MeSH concept]
- losartan potassium [MeSH concept]
Related MeSH Supplementary Concept(s)
- 1-pentanoyl-N-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)pyrrolidine-2-carboxamide [MeSH Supplementary Concept]
- 2-butyl-4-chloro-1-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-1H-imidazole-5-carboxaldehyde [MeSH Supplementary Concept]
- HM70186 [MeSH Supplementary Concept]
- V8 compound [MeSH Supplementary Concept]
- amlodipine-losartan drug combination [MeSH Supplementary Concept]
- hydrochlorothiazide, losartan drug combination [MeSH Supplementary Concept]
- losartan carboxylic acid [MeSH Supplementary Concept]
See also
- Valsartan [MeSH Descriptor]
See also inter- (CISMeF)
- Product containing losartan (medicinal product) [SNOMED CT concept]
- losartan [Pharmacological Root]
- losartan potassium [Substance BNPC]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Losartan [LOINC component]
- Losartan [NCIt concept]
- Losartan (substance) [SNOMED CT concept]
- Product containing losartan (medicinal product) [SNOMED CT concept]
- losartan [ATC Code]
- losartan [Pharmacological Root]
- losartan [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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