3-Iodobenzylguanidine

Preferred Label : 3-Iodobenzylguanidine;

MeSH definition : A guanidine analog with specific affinity for tissues of the sympathetic nervous system and related tumors. The radiolabeled forms are used as antineoplastic agents and radioactive imaging agents. (Merck Index, 12th ed) MIBG serves as a neuron-blocking agent which has a strong affinity for, and retention in, the adrenal medulla and also inhibits ADP-ribosyltransferase.;

MeSH synonym : mibg; m-iodobenzylguanidine; meta iodobenzylguanidine; meta-iodobenzylguanidine; iobenguane; m iodobenzylguanidine; 3 iodobenzylguanidine;

MeSH hyponym : 3-Iodobenzylguanidine, 125I labeled; iobenguane (131I); (3-Iodo-(131I)benzyl)guanidine; 3-Iodobenzylguanidine, 123I labeled; 125I Labeled 3-Iodobenzylguanidine; 3 Iodobenzylguanidine, 125I Labeled; 123I Labeled 3-Iodobenzylguanidine; 3 Iodobenzylguanidine, 123I Labeled;

MeSH Related Number : 3-Iodobenzylguanidine, 123I labeled; 3-Iodobenzylguanidine, 125I labeled; 74075-13-1 (125I labeled cpd); 76924-93-1 (123I labeled cpd); 77679-27-7 (3-Iodobenzylguanidine); iobenguane (131I); Q461L7AK4R;

Registry Number MeSH : 77679-27-7;

Related CAS MeSH : 74075-13-1 (3-Iodobenzylguanidine, 125I labeled); 76924-93-1 (3-Iodobenzylguanidine, 123I labeled); Q461L7AK4R (Iobenguane (131I));

Is substance : O;

UNII : 35MRW7B4AD;

InChIKey : PDWUPXJEEYOOTR-UHFFFAOYSA-N;

Details

Origin ID

D019797;

UMLS CUI

C0047506;

ATC code(s)
- iobenguane (123i) [ATC Code]
- iobenguane (131i) [ATC Code]
- iobenguane (131i) [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- I-131 MIBG [LOINC part]
- I-131 metaiodobenzylguanidine [Radlex concept]
- Iobenguane [NCIt concept]
- Iobenguane (substance) [SNOMED CT concept]
- Iobenguane I-131 [NCIt concept]
- Product containing iobenguane (131-I) (medicinal product) [SNOMED CT concept]
- iobenguane (131i) [ATC Code]
Pharmacological action(s)
- antineoplastic agents [MeSH Descriptor]
- enzyme inhibitors [MeSH Descriptor]
- radiopharmaceuticals [MeSH Descriptor]
Record concept(s)
- (3-Iodo-(131I)benzyl)guanidine [MeSH concept]
- 3-Iodobenzylguanidine [MeSH concept]
- 3-Iodobenzylguanidine, 123I labeled [MeSH concept]
- 3-Iodobenzylguanidine, 125I labeled [MeSH concept]
- iobenguane (131I) [MeSH concept]
Related MeSH Supplementary Concept(s)
- 4-amino-3-iodobenzylguanidine [MeSH Supplementary Concept]
- 4-hydroxy-3-iodobenzylguanidine [MeSH Supplementary Concept]
See also inter- (CISMeF)
- iobenguane (131i) [ATC Code]
Semantic type(s)
- Indicator, Reagent, or Diagnostic Aid [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
Validated automatic mappings to BTNT
- Iobenguane (123-I) (substance) [SNOMED CT concept]
- Iobenguane (131-I) (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

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