" /> tissue inhibitor of metalloproteinase-2 - CISMeF





Preferred Label : tissue inhibitor of metalloproteinase-2;

MeSH definition : A member of the family of TISSUE INHIBITOR OF METALLOPROTEINASES. It is a 21-kDa nonglycosylated protein found in tissue fluid and is secreted as a complex with progelatinase A by human fibroblast and uncomplexed from alveolar macrophages. An overexpression of TIMP-2 has been shown to inhibit invasive and metastatic activity of tumor cells and decrease tumor growth in vivo.;

MeSH synonym : metalloproteinase-2 tissue inhibitor; timp-2; tissue inhibitor of metalloproteinase 2;

Registry Number MeSH : 127497-59-0;

Is substance : O;

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A member of the family of TISSUE INHIBITOR OF METALLOPROTEINASES. It is a 21-kDa nonglycosylated protein found in tissue fluid and is secreted as a complex with progelatinase A by human fibroblast and uncomplexed from alveolar macrophages. An overexpression of TIMP-2 has been shown to inhibit invasive and metastatic activity of tumor cells and decrease tumor growth in vivo.

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27/07/2025


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