Preferred Label : glycyrrhizic acid;
MeSH definition : A widely used anti-inflammatory agent isolated from the licorice root. It is metabolized
to GLYCYRRHETINIC ACID, which inhibits 11-BETA-HYDROXYSTEROID DEHYDROGENASES and other
enzymes involved in the metabolism of CORTICOSTEROIDS. Therefore, glycyrrhizic acid,
which is the main and sweet component of licorice, has been investigated for its ability
to cause hypermineralocorticoidism with sodium retention and potassium loss, edema,
increased blood pressure, as well as depression of the renin-angiotensin-aldosterone
system.;
MeSH synonym : acid, glycyrrhizic; acid, glycyrrhizinic; glycyrrhizinic acid; glycyrrhizin;
MeSH hyponym : dipotassium glycyrrhizinate; diammonium glycyrrhizinate; zinc glycyrrhizate; Glycyrrhizate, Zinc; Glycyrrhizinate, Diammonium; Glycyrrhizinate, Dipotassium;
MeSH CAS label : alpha-D-glucopyranosiduronic acid, (3 beta,20 beta)-20-carboxy-11-oxo-30-norolean-12-en-3-yl
2-O-beta-D-glucopyranuronosyl-;
MeSH Related Number : 1405-86-3 (Glycyrrhizic acid); dipotassium glycyrrhizinate; CA2Y0FE3FX;
Registry Number MeSH : 1405-86-3;
Related CAS MeSH : CA2Y0FE3FX (Dipotassium glycyrrhizinate);
MeSH annotation : do not confuse with GLYCYRRHETINIC ACID;
Wikipedia link : https://en.wikipedia.org/wiki/Glycyrrhizin;
Codes EINECS : 215-785-7;
Is substance : O;
UNII : 6FO62043WK;
InChIKey : LPLVUJXQOOQHMX-QWBHMCJMSA-N;
Origin ID : D019695;
UMLS CUI : C0061751;
ATC code(s)
- Allowable qualifiers
- CISMeF manual mappings
- Currated CISMeF NLP mapping
- Pharmacological action(s)
- Record concept(s)
- Related MeSH Supplementary Concept(s)
- viusid [MeSH Supplementary Concept]
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
A widely used anti-inflammatory agent isolated from the licorice root. It is metabolized
to GLYCYRRHETINIC ACID, which inhibits 11-BETA-HYDROXYSTEROID DEHYDROGENASES and other
enzymes involved in the metabolism of CORTICOSTEROIDS. Therefore, glycyrrhizic acid,
which is the main and sweet component of licorice, has been investigated for its ability
to cause hypermineralocorticoidism with sodium retention and potassium loss, edema,
increased blood pressure, as well as depression of the renin-angiotensin-aldosterone
system.
