" /> phosphatidylinositol 4,5-diphosphate - CISMeF





Preferred Label : phosphatidylinositol 4,5-diphosphate;

MeSH definition : A phosphoinositide present in all eukaryotic cells, particularly in the plasma membrane. It is the major substrate for receptor-stimulated phosphoinositidase C, with the consequent formation of inositol 1,4,5-triphosphate and diacylglycerol, and probably also for receptor-stimulated inositol phospholipid 3-kinase. (Kendrew, The Encyclopedia of Molecular Biology, 1994);

MeSH synonym : ptins 4,5-p2; 4,5-biphosphate, phosphatidylinositol; 4,5-diphosphate, phosphatidylinositol; ptdinsp2; phosphatidylinositol 4,5-biphosphate; phosphatidylinositol 4,5 biphosphate; phosphatidylinositol phosphate, PtdIns(4,5)P2; PtdIns(4,5)P2; Phosphatidylinositol-4,5-Biphosphate; PtdInsP; phosphatidylinositol 4,5 diphosphate;

CISMeF synonym : phosphatidylinositol 4,5 bisphosphate; pip2; phosphatidylinositol-4,5-bisphosphate;

Is substance : O;

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A phosphoinositide present in all eukaryotic cells, particularly in the plasma membrane. It is the major substrate for receptor-stimulated phosphoinositidase C, with the consequent formation of inositol 1,4,5-triphosphate and diacylglycerol, and probably also for receptor-stimulated inositol phospholipid 3-kinase. (Kendrew, The Encyclopedia of Molecular Biology, 1994)

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09/07/2025


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