Preferred Label : phosphatidylinositol 4,5-diphosphate;
MeSH definition : A phosphoinositide present in all eukaryotic cells, particularly in the plasma membrane.
It is the major substrate for receptor-stimulated phosphoinositidase C, with the consequent
formation of inositol 1,4,5-triphosphate and diacylglycerol, and probably also for
receptor-stimulated inositol phospholipid 3-kinase. (Kendrew, The Encyclopedia of
Molecular Biology, 1994);
MeSH synonym : ptins 4,5-p2; 4,5-biphosphate, phosphatidylinositol; 4,5-diphosphate, phosphatidylinositol; ptdinsp2; phosphatidylinositol 4,5-biphosphate; phosphatidylinositol 4,5 biphosphate; phosphatidylinositol phosphate, PtdIns(4,5)P2; PtdIns(4,5)P2; Phosphatidylinositol-4,5-Biphosphate; PtdInsP; phosphatidylinositol 4,5 diphosphate;
CISMeF synonym : phosphatidylinositol 4,5 bisphosphate; pip2; phosphatidylinositol-4,5-bisphosphate;
Is substance : O;
Origin ID : D019269;
UMLS CUI : C0070798;
Allowable qualifiers
Automatic exact mappings (from CISMeF team)
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UMLS correspondences (same concept)
A phosphoinositide present in all eukaryotic cells, particularly in the plasma membrane.
It is the major substrate for receptor-stimulated phosphoinositidase C, with the consequent
formation of inositol 1,4,5-triphosphate and diacylglycerol, and probably also for
receptor-stimulated inositol phospholipid 3-kinase. (Kendrew, The Encyclopedia of
Molecular Biology, 1994)