phosphatidylinositol 4,5-diphosphate

Preferred Label : phosphatidylinositol 4,5-diphosphate;

MeSH definition : A phosphoinositide present in all eukaryotic cells, particularly in the plasma membrane. It is the major substrate for receptor-stimulated phosphoinositidase C, with the consequent formation of inositol 1,4,5-triphosphate and diacylglycerol, and probably also for receptor-stimulated inositol phospholipid 3-kinase. (Kendrew, The Encyclopedia of Molecular Biology, 1994);

MeSH synonym : ptins 4,5-p2; 4,5-biphosphate, phosphatidylinositol; 4,5-diphosphate, phosphatidylinositol; ptdinsp2; phosphatidylinositol 4,5-biphosphate; phosphatidylinositol 4,5 biphosphate; phosphatidylinositol phosphate, PtdIns(4,5)P2; PtdIns(4,5)P2; Phosphatidylinositol-4,5-Biphosphate; PtdInsP; phosphatidylinositol 4,5 diphosphate;

CISMeF synonym : phosphatidylinositol 4,5 bisphosphate; pip2; phosphatidylinositol-4,5-bisphosphate;

Is substance : O;

Details

Origin ID

D019269;

UMLS CUI

C0070798;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Phosphatidylinositol 4,5-bisphosphate [NCIt concept]
- Proximal Interphalangeal Joint 2 [NCIt concept]
Record concept(s)
- phosphatidylinositol 4,5-Diphosphate [MeSH concept]
Related MeSH Supplementary Concept(s)
- dioctanoyl-phosphatidylinositol 4,5-bisphosphate [MeSH Supplementary Concept]
- phosphatidylinositol-3,4,5-trisphosphorothioate [MeSH Supplementary Concept]
Semantic type(s)
- Biologically Active Substance [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Phosphatidylinositol 4,5-bisphosphate [NCIt concept]

Keyword's position in hierarchy(ies) :

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