Preferred Label : genes, erbb;
MeSH definition : Retrovirus-associated DNA sequences (erbB) originally isolated from, or related to,
the avian erythroblastosis virus (AEV). These genes code for the epidermal growth
factor receptor (EGFR) family of receptors which is important in the control of normal
cell proliferation and in the pathogenesis of human cancer. The genes include erbB-1
(GENES, ERBB-1), erbB-2 (GENES, ERBB-2), and erbB-3, all of which show abnormalities
of expression in various human neoplasms.;
MeSH synonym : erbb gene; erbb genes;
CISMeF synonym : erbb;
MeSH hyponym : erbB-3 genes; c-erbB-3 genes; Genes, c-erbB-3; c erbB 3 Genes; c-erbB-3 Gene; erbB 3 Genes; erbB-3 Gene;
MeSH annotation : spell in titles & translations as erbB; GENES, ERBB-1 & GENES, ERBB-2 are also available;
Origin ID : D018815;
UMLS CUI : C0243036;
Allowable qualifiers
- Automatic exact mappings (from CISMeF team)
- Record concept(s)
- See also
- Semantic type(s)
- UMLS correspondences (same concept)
Retrovirus-associated DNA sequences (erbB) originally isolated from, or related to,
the avian erythroblastosis virus (AEV). These genes code for the epidermal growth
factor receptor (EGFR) family of receptors which is important in the control of normal
cell proliferation and in the pathogenesis of human cancer. The genes include erbB-1
(GENES, ERBB-1), erbB-2 (GENES, ERBB-2), and erbB-3, all of which show abnormalities
of expression in various human neoplasms.
