helix-loop-helix motifs

Preferred Label : helix-loop-helix motifs;

MeSH definition : Recurring supersecondary structures characterized by 20 amino acids folding into two alpha helices connected by a non-helical loop segment. They are found in many sequence-specific DNA-BINDING PROTEINS and in CALCIUM-BINDING PROTEINS.;

MeSH synonym : motif, helix-loop-helix; motif, hlh; hlh motifs; motifs, hlh; helix-loop-helix motif; motifs, helix-loop-helix; motifs, helix loop helix; hlh motif; helix loop helix motifs; Helix-Loop-Helix Domains; Helix Loop Helix Domains; Helix Loop Helix Motif; Helix-Loop-Helix Domain; Helix Loop Helix Domain;

MeSH annotation : do not confuse with HELIX-TURN-HELIX MOTIFS;

Details

Origin ID

D018257;

UMLS CUI

C0206678;

Allowable qualifiers
- drug effects [MeSH Qualifier]
- genetics [MeSH Qualifier]
- immunology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
Currated CISMeF NLP mapping
- Helix-Loop-Helix Domain [NCIt concept]
Indexing information
- AIG1 protein, arabidopsis [MeSH Supplementary Concept]
- AMS protein, arabidopsis [MeSH Supplementary Concept]
- ARNT2 protein, xenopus [MeSH Supplementary Concept]
- ASCL2 protein, Xenopus [MeSH Supplementary Concept]
- ASCL3 protein, human [MeSH Supplementary Concept]
- ASCL4 protein, human [MeSH Supplementary Concept]
- ATOH7 protein, Xenopus [MeSH Supplementary Concept]
- ATOH7 protein, human [MeSH Supplementary Concept]
- ATOH8 protein, human [MeSH Supplementary Concept]
- ATR2 protein, arabidopsis [MeSH Supplementary Concept]
- Ascl3 protein, mouse [MeSH Supplementary Concept]
- Atoh7 protein, mouse [MeSH Supplementary Concept]
- Atoh8 protein, mouse [MeSH Supplementary Concept]
- B-Peru protein, zea mays [MeSH Supplementary Concept]
- BETA1 protein, cricetinae [MeSH Supplementary Concept]
- BETA3 protein, cricetinae [MeSH Supplementary Concept]
- BHLHA9 protein, human [MeSH Supplementary Concept]
- BMAL2 protein, human [MeSH Supplementary Concept]
- BMD2 protein, branchiostoma floridae [MeSH Supplementary Concept]
- Bhlha15 protein, mouse [MeSH Supplementary Concept]
- Bhlha15 protein, rat [MeSH Supplementary Concept]
- Bhlhb9 protein, rat [MeSH Supplementary Concept]
- Bhlhe41 protein, rat [MeSH Supplementary Concept]
- CASH-1 protein, gallus gallus [MeSH Supplementary Concept]
- CASH4 protein, gallus gallus [MeSH Supplementary Concept]
- CCNDBP1 protein, human [MeSH Supplementary Concept]
- CPH2 protein, candida albicans [MeSH Supplementary Concept]
- CTF4 protein, gallus gallus [MeSH Supplementary Concept]
- ClaR protein, streptomyces clavuligerus [MeSH Supplementary Concept]
- CsASH1 protein, cupiennius salei [MeSH Supplementary Concept]
- CsASH2 protein, cupiennius salei [MeSH Supplementary Concept]
- DIP1 protein, arabidopsis [MeSH Supplementary Concept]
- DISCO interacting protein 1, drosophila [MeSH Supplementary Concept]
- Da protein, Drosophila [MeSH Supplementary Concept]
- E(spl)m3-HLH protein, Drosophila [MeSH Supplementary Concept]
- E(spl)m8-HLH protein, Drosophila [MeSH Supplementary Concept]
- E(spl)mbeta-HLH protein, Drosophila [MeSH Supplementary Concept]
- E(spl)mdelta-HLH protein, Drosophila [MeSH Supplementary Concept]
- E(spl)mgamma-HLH protein, Drosophila [MeSH Supplementary Concept]
- ESC1 protein, S pombe [MeSH Supplementary Concept]
- ESR-5 protein, xenopus [MeSH Supplementary Concept]
- ETC2 protein, arabidopsis [MeSH Supplementary Concept]
- Esr1 protein, xenopus [MeSH Supplementary Concept]
- ExsA protein, bacteria [MeSH Supplementary Concept]
- FIT1 protein, arabidopsis [MeSH Supplementary Concept]
- GL3 protein, arabidopsis [MeSH Supplementary Concept]
- GPRASP3 protein, human [MeSH Supplementary Concept]
- HAND2 protein, human [MeSH Supplementary Concept]
- HEB protein, rat [MeSH Supplementary Concept]
- HELT protein, human [MeSH Supplementary Concept]
- HES7 protein, human [MeSH Supplementary Concept]
- HEY1 protein, Xenopus [MeSH Supplementary Concept]
- HEY2 protein, human [MeSH Supplementary Concept]
- HLH-14 protein, C elegans [MeSH Supplementary Concept]
- HLH-17 protein, C elegans [MeSH Supplementary Concept]
- HLH-3 protein, C elegans [MeSH Supplementary Concept]
- HLH1.4 protein, vertebrate [MeSH Supplementary Concept]
- HLH3B protein, drosophila [MeSH Supplementary Concept]
- HLH4C protein, drosophila [MeSH Supplementary Concept]
- Hand2 protein, mouse [MeSH Supplementary Concept]
- Hand2 protein, rat [MeSH Supplementary Concept]
- Hand2 protein, xenopus [MeSH Supplementary Concept]
- Hcls1 protein, mouse [MeSH Supplementary Concept]
- Helt protein, rat [MeSH Supplementary Concept]
- Her11 protein, zebrafish [MeSH Supplementary Concept]
- Her3 protein, zebrafish [MeSH Supplementary Concept]
- Her6 protein, zebrafish [MeSH Supplementary Concept]
- Hes1 protein, mouse [MeSH Supplementary Concept]
- Hes1 protein, rat [MeSH Supplementary Concept]
- Hes2 protein, rat [MeSH Supplementary Concept]
- Hes3 protein, mouse [MeSH Supplementary Concept]
- Hes3 protein, rat [MeSH Supplementary Concept]
- Hes7 protein, mouse [MeSH Supplementary Concept]
- Hif3a protein, mouse [MeSH Supplementary Concept]
- HlyX protein, actinobacillus pleuropneumoniae [MeSH Supplementary Concept]
- ID3 protein, human [MeSH Supplementary Concept]
- ID4 protein, human [MeSH Supplementary Concept]
- IEBP1 protein, rat [MeSH Supplementary Concept]
- INDEHISCENT protein, arabidopsis [MeSH Supplementary Concept]
- Id3 protein, rat [MeSH Supplementary Concept]
- Id3 protein, xenopus [MeSH Supplementary Concept]
- Id4 protein, rat [MeSH Supplementary Concept]
- Id4 protein, xenopus [MeSH Supplementary Concept]
- Idb3 protein, mouse [MeSH Supplementary Concept]
- Idb4 protein, mouse [MeSH Supplementary Concept]
- Itih4 protein, mouse [MeSH Supplementary Concept]
- KIDARI protein, arabidopsis [MeSH Supplementary Concept]
- LYL1 protein, human [MeSH Supplementary Concept]
- Lsr protein, rat [MeSH Supplementary Concept]
- Lyl1 protein, mouse [MeSH Supplementary Concept]
- MET protein, Drosophila [MeSH Supplementary Concept]
- MLXIP protein, human [MeSH Supplementary Concept]
- MNT protein, human [MeSH Supplementary Concept]
- MXI1 protein, human [MeSH Supplementary Concept]
- Mapk8ip1 protein, rat [MeSH Supplementary Concept]
- Meso1 protein, mesocricetus auratus [MeSH Supplementary Concept]
- Mesp1 protein, mouse [MeSH Supplementary Concept]
- Mesp2 protein, mouse [MeSH Supplementary Concept]
- MondoA protein, rat [MeSH Supplementary Concept]
- Msgn1 protein, Xenopus [MeSH Supplementary Concept]
- Msgn1 protein, mouse [MeSH Supplementary Concept]
- NEUROD1 protein, human [MeSH Supplementary Concept]
- NEUROD2 protein, human [MeSH Supplementary Concept]
- NEUROD4 protein, Xenopus [MeSH Supplementary Concept]
- NEUROD6 protein, human [MeSH Supplementary Concept]
- NEUROG1 protein, human [MeSH Supplementary Concept]
- NEUROG2 protein, human [MeSH Supplementary Concept]
- NEX protein, rat [MeSH Supplementary Concept]
- NHLH1 protein, human [MeSH Supplementary Concept]
- NHLH2 protein, human [MeSH Supplementary Concept]
- NPAS1 protein, human [MeSH Supplementary Concept]
- NPAS2 protein, human [MeSH Supplementary Concept]
- NPAS3 protein, human [MeSH Supplementary Concept]
- NUPR1 protein, Xenopus [MeSH Supplementary Concept]
- NUPR1 protein, human [MeSH Supplementary Concept]
- Nan-1D protein, arabidopsis [MeSH Supplementary Concept]
- NeuroM protein, chicken [MeSH Supplementary Concept]
- Neurod1 protein, rat [MeSH Supplementary Concept]
- Neurod2 protein, mouse [MeSH Supplementary Concept]
- Neurod2 protein, rat [MeSH Supplementary Concept]
- Neurod4 protein, mouse [MeSH Supplementary Concept]
- Neurod6 protein, mouse [MeSH Supplementary Concept]
- Neurod6 protein, rat [MeSH Supplementary Concept]
- Neurog2 protein, mouse [MeSH Supplementary Concept]
- Neurogenic differentiation factor 1 [MeSH Supplementary Concept]
- Nhlh2 protein, mouse [MeSH Supplementary Concept]
- NitR protein, rhodococcus rhodochrous [MeSH Supplementary Concept]
- Npas2 protein, mouse [MeSH Supplementary Concept]
- Npas3 protein, mouse [MeSH Supplementary Concept]
- Npas4 protein, rat [MeSH Supplementary Concept]
- Nulp1 protein, mouse [MeSH Supplementary Concept]
- Nupr1 protein, mouse [MeSH Supplementary Concept]
- Nupr1 protein, rat [MeSH Supplementary Concept]
- OLIG1 protein, human [MeSH Supplementary Concept]
- OLIG2 protein, human [MeSH Supplementary Concept]
- Olig1 protein, mouse [MeSH Supplementary Concept]
- Olig3 protein, mouse [MeSH Supplementary Concept]
- PAR1 protein, arabidopsis [MeSH Supplementary Concept]
- PAR2 protein, arabidopsis [MeSH Supplementary Concept]
- PCF1 protein, oryza sativa [MeSH Supplementary Concept]
- PCF2 protein, oryza sativa [MeSH Supplementary Concept]
- PIF4 protein, arabidopsis [MeSH Supplementary Concept]
- PIF5 protein, arabidopsis [MeSH Supplementary Concept]
- PIF6 protein, arabidopsis [MeSH Supplementary Concept]
- PIL5 protein, arabidopsis [MeSH Supplementary Concept]
- PIL6 protein, arabidopsis [MeSH Supplementary Concept]
- PLW-OSB1 protein, oryza sativa [MeSH Supplementary Concept]
- PLW-OSB2 protein, oryza sativa [MeSH Supplementary Concept]
- PRE1 protein, arabidopsis [MeSH Supplementary Concept]
- Pdrg1 protein, mouse [MeSH Supplementary Concept]
- Psmd9 protein, rat [MeSH Supplementary Concept]
- REB beta protein, rat [MeSH Supplementary Concept]
- RERJ1 protein, rice [MeSH Supplementary Concept]
- RGS2 protein, human [MeSH Supplementary Concept]
- RSF1 protein, arabidopsis [MeSH Supplementary Concept]
- RTG3 protein, S cerevisiae [MeSH Supplementary Concept]
- SCX protein, human [MeSH Supplementary Concept]
- SIM1 protein, Xenopus [MeSH Supplementary Concept]
- SIM1 protein, human [MeSH Supplementary Concept]
- SPT protein, arabidopsis [MeSH Supplementary Concept]
- SPZ1 protein, human [MeSH Supplementary Concept]
- SREBP protein, Drosophila [MeSH Supplementary Concept]
- SUM1 protein, sea urchin [MeSH Supplementary Concept]
- Sim1 protein, mouse [MeSH Supplementary Concept]
- Sim1 protein, rat [MeSH Supplementary Concept]
- SocC protein, myxococcus xanthus [MeSH Supplementary Concept]
- Sohlh1 protein, mouse [MeSH Supplementary Concept]
- Srebf2 protein, rat [MeSH Supplementary Concept]
- StrR protein, streptomyces griseus [MeSH Supplementary Concept]
- TAL1 protein, Xenopus [MeSH Supplementary Concept]
- TCF15 protein, human [MeSH Supplementary Concept]
- TCF3 protein, human [MeSH Supplementary Concept]
- TCFL5 protein, human [MeSH Supplementary Concept]
- TFDP2 protein, human [MeSH Supplementary Concept]
- TFPT protein, human [MeSH Supplementary Concept]
- TT8 protein, arabidopsis [MeSH Supplementary Concept]
- TWIST2 protein, human [MeSH Supplementary Concept]
- Tcf15 protein, mouse [MeSH Supplementary Concept]
- Tcf21 protein, Xenopus [MeSH Supplementary Concept]
- Tcf3 protein, mouse [MeSH Supplementary Concept]
- Tcf4 protein, rat [MeSH Supplementary Concept]
- Tcfe3 protein, mouse [MeSH Supplementary Concept]
- Tcfl5 protein, mouse [MeSH Supplementary Concept]
- Tfdp2 protein, mouse [MeSH Supplementary Concept]
- Twist2 protein, mouse [MeSH Supplementary Concept]
- Uncx protein, rat [MeSH Supplementary Concept]
- WBSCR11 protein, xenopus [MeSH Supplementary Concept]
- YidZ protein, E coli [MeSH Supplementary Concept]
- abf-1 protein, C elegans [MeSH Supplementary Concept]
- alphatalpha protein, synthetic [MeSH Supplementary Concept]
- amos protein, drosophila [MeSH Supplementary Concept]
- arnt2 protein, zebrafish [MeSH Supplementary Concept]
- ase protein, Drosophila [MeSH Supplementary Concept]
- ato protein, drosophila [MeSH Supplementary Concept]
- atoh1b protein, zebrafish [MeSH Supplementary Concept]
- bHLH121 protein, Arabidopsis [MeSH Supplementary Concept]
- bHLHA9 protein, mouse [MeSH Supplementary Concept]
- bhlhe22 protein, zebrafish [MeSH Supplementary Concept]
- cato protein, drosophila [MeSH Supplementary Concept]
- cyc protein, Drosophila [MeSH Supplementary Concept]
- dpn protein, drosophila [MeSH Supplementary Concept]
- eIF3m protein, Drosophila [MeSH Supplementary Concept]
- emc protein, drosophila [MeSH Supplementary Concept]
- fhlA protein, E coli [MeSH Supplementary Concept]
- figla protein, mouse [MeSH Supplementary Concept]
- foxi1 protein, zebrafish [MeSH Supplementary Concept]
- gene 3 protein, lactobacillus casei bacteriophage A2 [MeSH Supplementary Concept]
- grainin 1 protein, entamoeba histolytica [MeSH Supplementary Concept]
- grainin 2 protein, entamoeba histolytica [MeSH Supplementary Concept]
- hairy protein, drosophila [MeSH Supplementary Concept]
- hairy protein, insect [MeSH Supplementary Concept]
- hairy, HRT1 protein [MeSH Supplementary Concept]
- hand protein, drosophila [MeSH Supplementary Concept]
- hand2 protein, zebrafish [MeSH Supplementary Concept]
- helix-loop-helix protein, eHAND [MeSH Supplementary Concept]
- helt protein, mouse [MeSH Supplementary Concept]
- her4.1 protein, zebrafish [MeSH Supplementary Concept]
- hes7.1 protein, Xenopus [MeSH Supplementary Concept]
- hes7.2 protein, Xenopus [MeSH Supplementary Concept]
- hey protein, drosophila [MeSH Supplementary Concept]
- hey2 protein, zebrafish [MeSH Supplementary Concept]
- l(1)sc protein, Drosophila [MeSH Supplementary Concept]
- mespaa protein, zebrafish [MeSH Supplementary Concept]
- mespba protein, zebrafish [MeSH Supplementary Concept]
- mnt protein, mouse [MeSH Supplementary Concept]
- msc protein, mouse [MeSH Supplementary Concept]
- msgn1 protein, zebrafish [MeSH Supplementary Concept]
- mych protein, zebrafish [MeSH Supplementary Concept]
- myogenin protein, oncorhynchus mykiss [MeSH Supplementary Concept]
- net protein, drosophila [MeSH Supplementary Concept]
- neurod4 protein, zebrafish [MeSH Supplementary Concept]
- neurog1 protein, zebrafish [MeSH Supplementary Concept]
- neurogenin, xenopus [MeSH Supplementary Concept]
- olig2 protein, zebrafish [MeSH Supplementary Concept]
- photoactivatable flavocytochrome molecular maquette protein, synthetic [MeSH Supplementary Concept]
- ref-1 protein, C elegans [MeSH Supplementary Concept]
- sage protein, drosophila [MeSH Supplementary Concept]
- scx protein, mouse [MeSH Supplementary Concept]
- scx protein, rat [MeSH Supplementary Concept]
- tal1 protein, zebrafish [MeSH Supplementary Concept]
- tgo protein, Drosophila [MeSH Supplementary Concept]
- tx protein, Drosophila [MeSH Supplementary Concept]
- vis protein, bacteriophage P4 [MeSH Supplementary Concept]
- zp3b protein, zebrafish [MeSH Supplementary Concept]
Ne pas confondre avec
- helix-turn-helix motifs [MeSH Descriptor]
Record concept(s)
- Helix-Loop-Helix motifs [MeSH concept]
See also
- basic helix-loop-helix leucine zipper transcription factors [MeSH Descriptor]
- basic helix-loop-helix transcription factors [MeSH Descriptor]
- dna-binding proteins [MeSH Descriptor]
See also (suggested by CISMeF)
- helix-turn-helix motifs [MeSH Descriptor]
Semantic type(s)
- Spatial Concept [UMLS semantic type]
UMLS correspondences (same concept)
- Helix-Loop-Helix Domain [NCIt concept]

Keyword's position in hierarchy(ies) :

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