receptors, leukotriene b4

Preferred Label : receptors, leukotriene b4;

MeSH definition : A class of cell surface leukotriene receptors with a preference for leukotriene B4. Leukotriene B4 receptor activation influences chemotaxis, chemokinesis, adherence, enzyme release, oxidative bursts, and degranulation in polymorphonuclear leukocytes. There are at least two subtypes of these receptors. Some actions are mediated through the inositol phosphate and diacylglycerol second messenger systems.;

MeSH synonym : leukotriene b4 receptor; leukotriene b4 receptors; receptors, ltb4; ltb4 receptors; ltb4 receptor; receptor, ltb4; receptor, leukotriene b4;

MeSH annotation : DF: RECEPT LEUKOTRIENE B4;

Is substance : O;

Details

Origin ID

D018102;

UMLS CUI

C0064847;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- LTB4R Gene [NCIt concept]
- Leukotriene b4 receptor [OMIM gene]
- leukotriene B4 receptor [HGNC gene]
Currated CISMeF NLP mapping
- Leukotriene B4 Receptor 1 [NCIt concept]
Indexing information
- 2-(2-morpholinocarbo-1-methylvinyl)-7-ethoxycarbopropoxybenzo(b)furan [MeSH Supplementary Concept]
- 2-acetyl-4-(2-diethylcarbamoyl-1-methylvinyl)-7-(1-phenylethoxy)benzo(b)furan [MeSH Supplementary Concept]
- 4-(3-(6-(3-benzo(1,3)dioxol-5-yl-5-thiophen-3-ylphenoxy)hexyl)-2-(2-carboxyethyl)phenoxy)butyric acid [MeSH Supplementary Concept]
- 4-(5-(4-(aminoiminomethyl)phenoxy)5,4pentyloxy)-3-methoxy-N,N,-bis(1-methylethyl)benzamide-2-butenedionate [MeSH Supplementary Concept]
- amelubant [MeSH Supplementary Concept]
- ro 0254094 [MeSH Supplementary Concept]
Record concept(s)
- receptors, leukotriene B4 [MeSH concept]
Related MeSH Supplementary Concept(s)
- LTB4R protein, human [MeSH Supplementary Concept]
- LTB4R2 protein, human [MeSH Supplementary Concept]
- Ltb4r protein, rat [MeSH Supplementary Concept]
- Ltb4r1 protein, mouse [MeSH Supplementary Concept]
- Ltb4r2 protein, mouse [MeSH Supplementary Concept]
See also (suggested by CISMeF)
- leukotriene b4 [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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