leukotriene b4

Preferred Label : leukotriene b4;

MeSH definition : The major metabolite in neutrophil polymorphonuclear leukocytes. It stimulates polymorphonuclear cell function (degranulation, formation of oxygen-centered free radicals, arachidonic acid release, and metabolism). (From Dictionary of Prostaglandins and Related Compounds, 1990);

MeSH synonym : leukotriene b-4; ltb4; b-4, leukotriene; leukotriene b 4;

MeSH Hyperonym : leukotrienes B; 5,12-diHETE; Leukotriene B; 5,12 diHETE; 5,12-HETE; 5,12 HETE;

MeSH CAS label : 6,8,10,14-Eicosatetraenoic acid, 5,12-dihydroxy-, (S-(R*,S*-(E,Z,E,Z)))-;

MeSH Related Number : 71160-24-2 (Leukotriene B4);

Registry Number MeSH : 71160-24-2;

MeSH annotation : /biosyn /physiol permitted; DF: note short X ref;

Is substance : O;

UNII : 1HGW4DR56D;

InChIKey : VNYSSYRCGWBHLG-AMOLWHMGSA-N;

Details

Origin ID

D007975;

UMLS CUI

C0023546;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Leukotriene B (substance) [SNOMED CT concept]
- Leukotriene B4 Measurement [NCIt concept]
- leukotriene b [SNOMED Notion]
Currated CISMeF NLP mapping
- Leukotriene B4 [NCIt concept]
Indexing information
- 10T024A compound [MeSH Supplementary Concept]
- A 93176 [MeSH Supplementary Concept]
- DPC11870-11 [MeSH Supplementary Concept]
- LTB4R protein, human [MeSH Supplementary Concept]
- LTB4R2 protein, human [MeSH Supplementary Concept]
- Ltb4r2 protein, mouse [MeSH Supplementary Concept]
- hinokiresinol [MeSH Supplementary Concept]
- obtusatic acid [MeSH Supplementary Concept]
Record concept(s)
- 5,12-diHETE [MeSH concept]
- leukotriene B4 [MeSH concept]
- leukotrienes B [MeSH concept]
Related MeSH Supplementary Concept(s)
- 12-methylleukotriene B3 [MeSH Supplementary Concept]
- 12-oxoleukotriene B4 [MeSH Supplementary Concept]
- 14,15-leukotriene B4 [MeSH Supplementary Concept]
- 18-carboxy-19,20-dinorleukotriene B4 [MeSH Supplementary Concept]
- 20-aldehyde leukotriene B4 [MeSH Supplementary Concept]
- 20-trifluoromethylleukotriene B4 [MeSH Supplementary Concept]
- 3-hydroxyleukotriene B4 [MeSH Supplementary Concept]
- 5,12,19-trihydroxy-6,8,10,14-eicosatetraenoic acid [MeSH Supplementary Concept]
- 5,12,20-trihydroxy-6,8,10,14-eicosatetraenoic acid [MeSH Supplementary Concept]
- 5,12-dihydroxy-6,8,14-eicosatrienoic acid [MeSH Supplementary Concept]
- 8,15-leukotriene B4 [MeSH Supplementary Concept]
- SC 45694 [MeSH Supplementary Concept]
- leukotriene B3 [MeSH Supplementary Concept]
- leukotriene B4 dimethylamide [MeSH Supplementary Concept]
- leukotriene B4 glucuronide [MeSH Supplementary Concept]
- leukotriene B5 [MeSH Supplementary Concept]
See also (suggested by CISMeF)
- receptors, leukotriene b4 [MeSH Descriptor]
Semantic type(s)
- Biologically Active Substance [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Leukotriene B4 [LOINC component]
- Leukotriene B4 [NCIt concept]

Keyword's position in hierarchy(ies) :

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