leukotriene d4

Preferred Label : leukotriene d4;

MeSH definition : One of the biologically active principles of SRS-A. It is generated from LEUKOTRIENE C4 after partial hydrolysis of the peptide chain, i.e., cleavage of the gamma-glutamyl portion. Its biological actions include stimulation of vascular and nonvascular smooth muscle, and increases in vascular permeability. (From Dictionary of Prostaglandins and Related Compounds, 1990);

MeSH synonym : leukotriene d-4; leukotriene d 4; LTD4;

MeSH Hyperonym : leukotrienes D; Leukotriene D;

MeSH CAS label : glycine, N-(S-(1-(4-carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl)-L-cysteinyl)-, (R-(R*,S*-(E,E,Z,Z)))-;

Registry Number MeSH : 73836-78-9;

MeSH annotation : /biosyn /physiol permitted; DF: note short X ref;

Is substance : O;

Details

Origin ID

D017998;

UMLS CUI

C0023544;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Arabic numeral 4 (qualifier value) [Inactive SNOMED CT concept]
- Leukotriene D (substance) [SNOMED CT concept]
- Leukotriene D4 [NCIt concept]
- Leukotriene D4 Measurement [NCIt concept]
- leukotriene c [SNOMED Notion]
- leukotriene d [SNOMED Notion]
Record concept(s)
- leukotriene D4 [MeSH concept]
- leukotrienes D [MeSH concept]
Related MeSH Supplementary Concept(s)
- 14-cysteinylglycyl-15-hydroxy-5,8,10,12-eicosatetraenoic acid [MeSH Supplementary Concept]
- iodinated azido-leukotriene D4 [MeSH Supplementary Concept]
Semantic type(s)
- Biologically Active Substance [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Leukotriene D4 [NCIt concept]

Keyword's position in hierarchy(ies) :

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