Preferred Label : leuprolide;

MeSH definition : A potent synthetic long-acting agonist of GONADOTROPIN-RELEASING HORMONE that regulates the synthesis and release of pituitary gonadotropins, LUTEINIZING HORMONE and FOLLICLE STIMULATING HORMONE.;

MeSH synonym : leuprorelin;

CISMeF synonym : 88793-81-1 (Leuprolide acetate);

MeSH hyponym : enantone; leuprolide, (L-Leu)-Isomer; leuprolide, (DL-Leu)-Isomer; A-43818; lupron; leuprolide acetate; TAP-144; leuprolide monoacetate; Acetate, Leuprolide; Monoacetate, Leuprolide; TAP 144; TAP144; A 43818; A43818;

MeSH CAS label : luteinizing hormone-releasing factor (pig), 6-D-leucine-9-(N-ethyl-L-prolinamide)-10-deglycinamide-;

MeSH Related Number : leuprolide acetate; leuprolide monoacetate; leuprolide, (L-Leu)-Isomer; leuprolide, (DL-Leu)-Isomer; 53714-56-0 (Leuprolide); 54785-87-4 ((L-Leu)-isomer); 61911-90-8 ((DL-Leu)-isomer); 74381-53-6 (monoacetate); 88793-81-1 (acetate); 37JNS02E7V;

Registry Number MeSH : 53714-56-0;

Related CAS MeSH : 74381-53-6 (Leuprolide monoacetate); 54785-87-4 (Leuprolide, (L-Leu)-Isomer); 61911-90-8 (Leuprolide, (DL-Leu)-Isomer); 37JNS02E7V (Leuprolide acetate);

Wikipedia link : https://en.wikipedia.org/wiki/Leuprorelin;

Is substance : O;

UNII : EFY6W0M8TG;

InChIKey : GFIJNRVAKGFPGQ-LIJARHBVSA-N;

Details


Main resources

You can consult :

A potent synthetic long-acting agonist of GONADOTROPIN-RELEASING HORMONE that regulates the synthesis and release of pituitary gonadotropins, LUTEINIZING HORMONE and FOLLICLE STIMULATING HORMONE.

https://www.has-sante.fr/jcms/p_3445467/fr/leuproreline-zentiva-leuproreline-cancer-de-la-prostate
2023
false
false
false
France
treatment outcome
insurance, health, reimbursement
drug implants
Hormone sensitive prostate cancer (disorder)
leuprolide acetate
antineoplastic agents, hormonal
leuprorelin
evaluation of the transparency committee
prostatic neoplasms
leuprolide

---
https://www.cadth.ca/fr/mesylate-de-leuprolide
2022
false
false
false
false
Canada
French
English
drug information
prostatic neoplasms
leuprolide
antineoplastic agents, hormonal
neoplasms, hormone-dependent
palliative care

---
https://www.ema.europa.eu/en/medicines/human/EPAR/camcevi
2022
false
false
false
Netherlands
French
English
treatment outcome
syndication feed
summary of product characteristics
package leaflet
drug evaluation
leuprolide
leuprolide
prostatic neoplasms
neoplasms, hormone-dependent
advanced hormone-dependent prostate cancer
antineoplastic agents, hormonal
antineoplastic agents, hormonal
adult
drug approval
europe
aged
Delayed-Action preparations
injections, subcutaneous
drug interactions
Leuprolide Mesylate Injectable Suspension
Product containing only leuprorelin in parenteral dose form (medicinal product form)
leuprorelin
drug evaluation, preclinical

---
https://www.has-sante.fr/jcms/p_3399894/fr/enantone-lp-leuproreline-puberte-precoce-centrale
2022
false
false
false
France
Delayed-Action preparations
insurance, health, reimbursement
treatment outcome
injections, subcutaneous
leuprolide acetate
Product containing only leuprorelin in parenteral dose form (medicinal product form)
evaluation of the transparency committee
leuprolide
precocious puberty, central
puberty, precocious

---
https://www.has-sante.fr/jcms/p_3322982/fr/zeulide-leuproreline
2022
false
false
false
France
leuprolide acetate
leuprolide acetate
insurance, health, reimbursement
treatment outcome
leuprorelin
prostatic neoplasms
neoplasms, hormone-dependent
palliative care
advanced hormone-dependent prostate cancer
fibroid uterus
endometriosis
puberty, precocious
breast neoplasms
premenopause
antineoplastic agents, hormonal
Product containing only leuprorelin in parenteral dose form (medicinal product form)
evaluation of the transparency committee
leuprolide

---
https://ansm.sante.fr/tableau-marr/acetate-de-leuproreline
2021
false
false
false
France
French
guidelines for drug use
drug compounding
leuprolide acetate
antineoplastic agents, hormonal
injections, subcutaneous
leuprorelin
leuprolide

---
https://www.inesss.qc.ca/thematiques/medicaments/medicaments-evaluation-aux-fins-dinscription/extrait-davis-au-ministre/zeulide-depot-cancer-prostate-5136.html
2020
false
false
false
Canada
French
drug evaluation
leuprolide acetate
prostatic neoplasms
leuprolide

---
https://ansm.sante.fr/informations-de-securite/recommandations-pour-eviter-les-erreurs-de-reconstitution-et-dadministration-des-medicaments-a-base-de-leuproreline-injectable
2020
false
false
false
France
French
guidelines for drug use
letter
health personnel
administration of medication, nos
due to
injection, nos
base, nos
injections
health planning guidelines
administration
leuprolide
correspondence as topic
Administration
health
Injection moulding
medication errors
letter
organization and administration
health

---
https://www.ansm.sante.fr/actualites/leuproreline-injectable-eligard-enantone-lp-leptoprol-injections-a-realiser-exclusivement-par-des-professionnels-de-sante-ayant-une-bonne-connaissance-des-etapes-de-reconstitution-administration
2020
false
false
false
France
French
guidelines for drug use
eligard
health personnel
knowledge
enantone
injections
injection, nos
insight, nos
wellness state
acquaintance
Injection moulding
health
leuprolide
luprolide acetate gel depot
health

---
https://www.has-sante.fr/jcms/p_3159944/fr/leptoprol
2020
false
false
false
France
leuprolide
leuprolide acetate
leuprorelin
prostatic neoplasms
neoplasms, hormone-dependent
antineoplastic agents, hormonal
drug implants
insurance, health, reimbursement
treatment outcome
radiotherapy
prostatic neoplasms
neoplasms, hormone-dependent
evaluation of the transparency committee

---
https://www.has-sante.fr/portail/jcms/c_2894926/en/enantone-lp
2018
false
true
false
France
-
-
-
injections
treatment outcome
leuprorelin
prostatic neoplasms
puberty, precocious
endometriosis
breast neoplasms
neoplasms, hormone-dependent
fibroid uterus
insurance, health, reimbursement
evaluation of the transparency committee
leuprolide
leiomyoma

---
https://www.has-sante.fr/portail/jcms/c_2830032/fr/enantone-lp
2018
false
false
false
false
France
French
evaluation of the transparency committee
enantone
leuprolide

---
Eligard (leuprolide acetate): Reconstitution and administration errors and risk of lack of efficacy
http://www.hc-sc.gc.ca/dhp-mps/medeff/bulletin/hpiw-ivps_2017-01-page2-fra.php#mae
2017
false
false
false
Canada
French
English
drug compounding
pharmacovigilance note
canada
leuprolide acetate
medication errors
injections, subcutaneous
Incorrect route of drug administration
Delayed-Action preparations
prostatic neoplasms
Inappropriate reconstitution technique
Product preparation error
leuprorelin
leuprolide

---
https://www.has-sante.fr/portail/jcms/c_2772599/fr/leptoprol
2017
false
false
false
France
French
evaluation of the transparency committee
treatment outcome
Prefilled Syringe Dosage Form
leuprolide acetate
drug implants
leuprorelin
antineoplastic agents, hormonal
insurance, health, reimbursement
neoplasms, hormone-dependent
prostatic neoplasms
Advanced Malignant Neoplasm
palliative care
injections, subcutaneous
leuprolide

---
https://ansm.sante.fr/informations-de-securite/eligard-poudre-et-solvant-pour-solution-injectable-acetate-de-leuproreline-reevaluation-des-conditions-de-prescription-et-de-delivrance-realisation-dun-dosage-de-la-testosteronemie
2016
false
false
false
false
France
French
pharmacovigilance note
guidelines for drug use
medication errors
Inappropriate reconstitution technique
injections, subcutaneous
luprolide acetate gel depot
leuprorelin
antineoplastic agents, hormonal
Drug maladministration
drug prescriptions
continuity of patient care
Blood testosterone
testosterone
advanced hormone-dependent prostate cancer
prostatic neoplasms
neoplasms, hormone-dependent
leuprolide

---
http://www.has-sante.fr/portail/jcms/c_2055988/fr/enantone-lp
2015
false
false
France
French
evaluation of the transparency committee
enantone
leuprolide

---
http://www.has-sante.fr/portail/jcms/c_2055991/fr/enantone-lp
2015
false
false
France
French
evaluation of the transparency committee
enantone
leuprolide

---
http://www.has-sante.fr/portail/jcms/c_977221/enantone
http://www.has-sante.fr/portail/upload/docs/application/pdf/2010-08/enantone_-_ct-5460.pdf
2010
France
French
leuprolide
injections, subcutaneous
Delayed-Action preparations
-
prostatic neoplasms
antineoplastic agents, hormonal
leuprorelin
treatment outcome
evaluation of the transparency committee

---
http://www.aboutkidshealth.ca/Fr/HealthAZ/Drugs/Pages/Leuprolide.aspx
http://www.aboutkidshealth.ca/en/healthaz/drugs/pages/leuprolide.aspx?k=leuprolide
2010
Canada
French
English
child
leuprolide
leuprolide
injections
Delayed-Action preparations
puberty, precocious
menstruation disturbances
drug information
patient education handout

---
http://www.lecrat.eu/?s=Leupror%C3%A9line
2009
France
French
leuprolide
pregnancy
antineoplastic agents, hormonal
leuprorelin
drug information

---
http://www.has-sante.fr/portail/display.jsp?id=c_574452
http://www.has-sante.fr/portail/upload/docs/application/pdf/ct-4432_enantone.pdf
http://www.has-sante.fr/portail/upload/docs/application/pdf/2010-11/enantone_ct_4432.pdf
2007
France
English
French
Delayed-Action preparations
-
-
leuprorelin
insurance, health, reimbursement
prostatic neoplasms
endometriosis
puberty, precocious
breast neoplasms
neoplasms, hormone-dependent
leiomyoma
treatment outcome
leuprolide
injections, subcutaneous
antineoplastic agents, hormonal
injections, intramuscular
evaluation of the transparency committee

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10/06/2024


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