Preferred Label : misoprostol;
MeSH definition : A synthetic analog of natural prostaglandin E1. It produces a dose-related inhibition
of gastric acid and pepsin secretion, and enhances mucosal resistance to injury. It
is an effective anti-ulcer agent and also has oxytocic properties.;
CISMeF synonym : misoprostol searle brand; misoprostol heumann brand; searle brand of misoprostol; pharmacia spain brand of misoprostol; heumann brand of misoprostol; pharmacia brand of misoprostol; misoprostol pharmacia brand; apotex brand of misoprostol; misoprostol apotex brand; pfizer brand of misoprostol; misoprostol pfizer brand; grunenthal brand of misoprostol; misoprostol grunenthal brand; novopharm brand of misoprostol; misoprostol novopharm brand;
MeSH hyponym : SC-29333; Novo-Misoprostol; cytotec; glefos; Apo-Misoprostol; Novo Misoprostol; SC 29333; SC29333; Apo Misoprostol;
Related MeSH term : misoprostol, (11alpha,13E,16R)-Isomer; misoprostol, (11alpha,13E)-Isomer; misoprostol, (11alpha,13Z)-( -)-Isomer; misoprostol, (11beta,13E,16S)-Isomer; misoprostol, (11beta,13E,16R)-Isomer; misoprostol, (11beta,13E)-( -)-Isomer; SC-30249; misoprostol, (11alpha.13E,16S)-Isomer; SC 30249; SC30249;
MeSH CAS label : Prost-13-en-1-oic acid, 11,16-dihydroxy-16-methyl-9-oxo-, methyl ester, (11alpha,13E)-;
MeSH Related Number : misoprostol, (11alpha,13E)-Isomer; misoprostol, (11alpha.13E,16S)-Isomer; misoprostol, (11beta,13E)-( -)-Isomer; misoprostol, (11beta,13E,16R)-Isomer; misoprostol, (11beta,13E,16S)-Isomer; misoprostol, (11alpha,13Z)-( -)-Isomer; misoprostol, (11alpha,13E,16R)-Isomer; 58717-36-5 ((11beta,13E)-( -)-isomer); 58717-37-6 ((11alpha,13Z)-( -)-isomer); 59122-46-2 (Misoprostol); 59122-48-4 ((11alpha,13E,16R)-isomer); 59122-49-5 ((11alpha.13E,16S)-isomer); 59122-50-8 ((11beta,13E,16S)-isomer); 59122-51-9 ((11beta,13E,16R)-isomer); 92999-98-9 ((11alpha,13E)-isomer);
Registry Number MeSH : 59122-46-2;
Related CAS MeSH : 92999-98-9 (Misoprostol, (11alpha,13E)-Isomer); 59122-49-5 (Misoprostol, (11alpha.13E,16S)-Isomer); 58717-36-5 (Misoprostol, (11beta,13E)-( -)-Isomer); 59122-51-9 (Misoprostol, (11beta,13E,16R)-Isomer); 59122-50-8 (Misoprostol, (11beta,13E,16S)-Isomer); 58717-37-6 (Misoprostol, (11alpha,13Z)-( -)-Isomer); 59122-48-4 (Misoprostol, (11alpha,13E,16R)-Isomer);
Wikipedia link : https://en.wikipedia.org/wiki/Misoprostol;
Is substance : O;
UNII : 0E43V0BB57;
InChIKey : OJLOPKGSLYJEMD-URPKTTJQSA-N;
Origin ID : D016595;
UMLS CUI : C0085174;
ATC code(s)
ATC code(s)
Allowable qualifiers
CISMeF manual mappings
Currated CISMeF NLP mapping
Pharmacological action(s)
Record concept(s)
Related MeSH Supplementary Concept(s)
See also inter- (CISMeF)
Semantic type(s)
UMLS correspondences (same concept)
Validated automatic mappings to BTNT
A synthetic analog of natural prostaglandin E1. It produces a dose-related inhibition
of gastric acid and pepsin secretion, and enhances mucosal resistance to injury. It
is an effective anti-ulcer agent and also has oxytocic properties.
https://ansm.sante.fr/tableau-atu-rtu/gymiso-200-microgrammes-comprime-2
2025
false
false
false
France
French
misoprostol
guidelines for drug use
abortion, Drug-Induced
abortifacient agents, nonsteroidal
misoprostol
drug therapy, combination
mifepristone
drug information
---
https://ansm.sante.fr/tableau-acces-derogatoire/gymiso-200-microgrammes-comprime-1
2024
false
false
false
France
French
misoprostol
mifepristone
drug information
continuity of patient care
Early Pregnancy Loss
---
https://www.has-sante.fr/jcms/p_3538951/fr/gymiso-misoprostol-interruption-medicale-de-grossesse
2024
false
false
false
France
evaluation of the transparency committee
disruption, nos
pregnancy, nos
misoprostol
abortion, therapeutic
pregnancy
misoprostol
---
https://sante.gouv.fr/actualites/presse/communiques-de-presse/article/misoprostol-le-ministre-de-la-sante-et-de-la-prevention-mobilise-pour-garantir
2023
France
scientific and technical information
misoprostol
preventive medicine
health
mobilization, nos
drug, nos
motion
homing behavior
misoprostol
drugs, essential
---
https://ansm.sante.fr/tableau-marr/misoprostol
2022
false
false
false
France
French
risk management
misoprostol
administration, oral
abortion, Drug-Induced
guidelines for drug use
patient education handout
teratogens
continuity of patient care
office visits
abortifacient agents, nonsteroidal
misoprostol
---
https://ansm.sante.fr/actualites/decision-du-21-02-2022-cadre-de-prescription-compassionnelle-du-misoprostol-dans-la-prise-en-charge-des-interruptions-volontaires-de-grossesses-medicamenteuses-a-la-8eme-et-a-la-9eme-semaine-damenorrhee
2022
false
false
false
France
French
legislation
misoprostol
abortion, Drug-Induced
---
https://www.has-sante.fr/jcms/p_3285514/fr/gymiso-misoone-misoprostol-/-mifegyne-mifepristone
2021
false
false
false
France
evaluation of the transparency committee
misoprostol
misoprostol
---
https://www.cochrane.org/fr/CD014484/PREG_misoprostol-faible-dose-administre-par-voie-orale-pour-le-declenchement-du-travail
2021
United Kingdom
review of literature
french abstract
asthenia
occupation, nos
due to
misoprostol
administration, oral
work
Labor ; manpower ; population
oral route
Administration
misoprostol
---
https://www.has-sante.fr/jcms/p_3223429/fr/interruption-volontaire-de-grossesse-par-methode-medicamenteuse-mise-a-jour
2021
false
France
French
abortion, Drug-Induced
insurance, health, reimbursement
mifepristone
misoprostol
administration, oral
continuity of patient care
pregnancy trimester, first
Gestation less than 9 weeks (finding)
office visits
abortion, induced
abortifacient agents, steroidal
misoprostol
drug therapy, combination
mifepristone
practice guideline
---
https://www.has-sante.fr/jcms/p_3190783/fr/misoone
2020
false
false
false
France
misoprostol
misoprostol
insurance, health, reimbursement
administration, oral
abortion on demand
cervical dilatation
Operative termination of pregnancy (procedure)
pregnancy trimester, first
evaluation of the transparency committee
abortion, legal
labor stage, first
---
https://www.sggg.ch/fileadmin/user_upload/63_Misoprostol_zur_Geburtseinleitung_franz.pdf
2019
false
false
false
Switzerland
oxytocics
misoprostol
Off-Label use
administration, oral
administration, intravaginal
switzerland
practice guideline
misoprostol
labor, induced
---
https://www.has-sante.fr/portail/jcms/c_2862078/fr/angusta
2018
false
false
false
false
France
French
evaluation of the transparency committee
misoprostol
misoprostol
administration, oral
treatment outcome
oxytocics
Induction of Labor
labor, induced
---
http://circulaire.legifrance.gouv.fr/index.php?action=afficherCirculaire&hit=1&r=43087
2018
false
false
false
France
French
drug recalls
abortion on demand
Off-Label use
misoprostol
labor, induced
abortion, therapeutic
abortion, spontaneous
Abortion early
fetal death
legislation
patient care management
misoprostol
gemeprost
misoprostol
gemeprost
legislation, drug
insurance, health, reimbursement
drug prescriptions
abortion, legal
alprostadil
alprostadil
---
http://www.has-sante.fr/portail/jcms/c_2735297/fr/misodel
2017
false
false
false
France
French
evaluation of the transparency committee
misoprostol
misoprostol
misoprostol
administration, intravaginal
Vaginal device (qualifier value)
insurance, health, reimbursement
labor, induced
oxytocics
oxytocics
Drug Induced Induction of Labor
---
Health Canada updates prescribing and dispensing information for Mifegymiso
https://canadiensensante.gc.ca/recall-alert-rappel-avis/hc-sc/2017/65034a-fra.php
https://canadiensensante.gc.ca/recall-alert-rappel-avis/hc-sc/2017/65030a-fra.php
2017
false
false
false
Canada
French
English
abortion, therapeutic
guidelines for drug use
patients guideline
administration, oral
administration, buccal
drug therapy, combination
mifepristone
mifepristone
drug labeling
abortifacient agents, steroidal
abortifacient agents, steroidal
misoprostol
misoprostol
abortifacient agents, nonsteroidal
abortifacient agents, nonsteroidal
risk management
informed consent
---
http://www.jogc.com/article/S1701-2163(16)39086-7/abstract
10.1016/j.jogc.2016.04.001
2016
false
false
true
Canada
French
practice guideline
abortion, induced
abortion, induced
methotrexate
misoprostol
abortion, induced
abortifacient agents
gestational age
pregnancy
Contraindications, Procedure
---
https://pharmacomedicale.org/medicaments/par-specialites/item/analogues-pge1-misoprostol
2016
false
false
false
France
French
drug information
misoprostol
anti-ulcer agents
prostaglandins E
misoprostol
misoprostol
alprostadil
---
MIFEGYMISO - Summary Basis of Decision
https://hpr-rps.hres.ca/reg-content/sommaire-motif-decision-detailTwo.php?lang=fr&linkID=SBD00239
2016
false
false
false
false
Canada
French
English
summary of product characteristics
canada
drug approval
drug antagonism
administration, oral
administration, buccal
misoprostol
misoprostol
mifepristone
mifepristone
abortifacient agents, nonsteroidal
abortifacient agents, nonsteroidal
abortifacient agents, steroidal
abortifacient agents, steroidal
abortion, Drug-Induced
risk assessment
drug evaluation
abortion, induced
---
http://www.has-sante.fr/portail/jcms/c_2572133/fr/cytotec
http://www.has-sante.fr/portail/jcms/c_1121561/cytotec
http://www.has-sante.fr/portail/jcms/c_400778/cytotec-200-microgrammes-comprime-secable-b/60-cip-328-786-4
2015
false
France
French
evaluation of the transparency committee
misoprostol
administration, oral
treatment outcome
insurance, health, reimbursement
anti-ulcer agents
misoprostol
peptic ulcer
peptic ulcer
peptic ulcer
anti-inflammatory agents, non-steroidal
---
http://www.has-sante.fr/portail/jcms/c_2040748/fr/artotec
http://www.has-sante.fr/portail/jcms/c_958811/artotec
2015
false
France
French
diclofenac, combinations
drug combinations
diclofenac
arthotec
misoprostol
administration, oral
insurance, health, reimbursement
anti-ulcer agents
antirheumatic agents
rheumatic diseases
anti-inflammatory agents, non-steroidal
evaluation of the transparency committee
---
http://www.has-sante.fr/portail/jcms/c_2008308/fr/misodel-misoprostol-prostaglandine-uterotonique
http://www.has-sante.fr/portail/jcms/c_2008308/fr/misodel
2015
false
false
false
France
French
administration, intravaginal
treatment outcome
misoprostol
misoprostol
oxytocics
labor, induced
guidelines for drug use
evaluation of the transparency committee
---
Par rapport aux inhibiteurs de la pompe à protons, pas d’avantage préventif des lésions
et complications gastroduodénales induites par un traitement indispensable par AINS
http://www.has-sante.fr/portail/jcms/c_2572133/fr/cytotec-misoprostol-prostaglandine
2015
true
France
French
evaluation of the transparency committee
guidelines for drug use
misoprostol
administration, oral
treatment outcome
insurance, health, reimbursement
anti-ulcer agents
misoprostol
peptic ulcer
peptic ulcer
peptic ulcer
anti-inflammatory agents, non-steroidal
---
https://smf.swisshealthweb.ch/fr/article/doi/fms.2015.02375/
2015
false
false
false
Switzerland
French
journal article
abortion, induced
mifepristone
misoprostol
abortifacient agents, nonsteroidal
abortifacient agents, steroidal
---
https://www.cochrane.org/fr/CD005998/
2015
false
false
false
France
United Kingdom
French
review of literature
preoperative care
hysteroscopy
postoperative complications
treatment outcome
misoprostol
oxytocics
french abstract
hysteroscopy
cervical ripening
---
http://dune.univ-angers.fr/documents/dune4446
2015
false
false
false
France
French
dissertations, academic
fetal death
stillbirth, nos
pregnancy
misoprostol
disruption, nos
fetal uterus
medical
misoprostol
sulprostone
pregnancy, nos
uterus
fetal intrapartum death
abortion, therapeutic
cicatricial
pregnancy
dinoprostone
---
http://www.has-sante.fr/portail/jcms/c_1727808/fr/artotec
2014
false
France
French
cardiovascular diseases
risk factors
guidelines for drug use
anti-inflammatory agents, non-steroidal
diclofenac, combinations
drug combinations
diclofenac
arthotec
misoprostol
administration, oral
insurance, health, reimbursement
anti-ulcer agents
antirheumatic agents
rheumatic diseases
anti-inflammatory agents, non-steroidal
diclofenac
evaluation of the transparency committee
---
http://base-donnees-publique.medicaments.gouv.fr/extrait.php?specid=61240145
2014
summary of product characteristics
misoprostol
tablets
---
http://www.cochrane.org/fr/CD003249
2014
false
true
false
United Kingdom
France
misoprostol
oxytocin
treatment outcome
review of literature
french abstract
postpartum hemorrhage
---
http://www.lecrat.eu/?s=Misoprostol
2013
France
French
drug information
pregnancy
misoprostol
oxytocics
abortifacient agents, nonsteroidal
misoprostol
---
http://www.cngof.asso.fr/data/RCP/CNGOF_2013_FINAL_AVIS_misoprostol.pdf
2013
France
French
misoprostol
misoprostol
Off-Label use
administration, intravaginal
administration, sublingual
treatment outcome
risk assessment
cervical dilatation
labor stage, first
oxytocics
extraction, obstetrical
abortion, spontaneous
administration, buccal
misoprostol
oxytocics
teratogens
embryo loss
pregnancy trimester, first
abortion, induced
abortion, therapeutic
fetal death
pregnancy trimester, second
pregnancy trimester, third
cervical ripening
postpartum hemorrhage
hysteroscopy
practice guideline
guidelines for drug use
Obstetrician (occupation)
Gynecologist (occupation)
---
http://www.cochrane.org/fr/CD008982
2013
United Kingdom
France
French
review of literature
treatment outcome
morbidity
maternal mortality
misoprostol
postpartum period
postnatal care
postpartum hemorrhage
postpartum hemorrhage
postpartum hemorrhage
misoprostol
french abstract
---
http://www.has-sante.fr/portail/jcms/c_1701297/fr/misoone-400-g
http://www.has-sante.fr/portail/jcms/c_1716177/fr/misoone16102013avisct12961
2013
false
France
French
administration, oral
misoprostol
misoprostol
misoprostol
adult
abortifacient agents, nonsteroidal
abortifacient agents, nonsteroidal
abortion, Drug-Induced
abortion, induced
evaluation of the transparency committee
therapeutic equivalency
treatment outcome
risk management
product surveillance, postmarketing
guidelines for drug use
---
https://www.cochrane.org/fr/CD000494/prostaglandines-dans-la-prevention-de-lhemorragie-du-post-partum
2012
false
United Kingdom
France
French
french abstract
review of literature
postpartum hemorrhage
treatment outcome
prostaglandins
misoprostol
labor stage, third
---
http://dumas.ccsd.cnrs.fr/dumas-00717192
2012
France
dissertations, academic
misoprostol
prospective studies
hospitals, university
achievement
cervical ripening
---
http://www.cochrane.org/fr/CD005216
2011
false
true
false
France
United Kingdom
abortion, induced
pregnancy
misoprostol
mifepristone
review of literature
french abstract
pregnancy trimester, second
---
http://www.has-sante.fr/portail/jcms/c_961137/interruption-volontaire-de-grossesse-par-methode-medicamenteuse
http://www.has-sante.fr/portail/jcms/c_1049424/ivg-methode-medicamenteuse-argumentaire-mel
2011
true
France
French
abortion, induced
abortifacient agents, steroidal
misoprostol
prostaglandins
drug therapy, combination
misoprostol
mifepristone
mifepristone
abortion, induced
practice guideline
---
http://www.cochrane.org/fr/CD004221
2010
false
true
false
United Kingdom
France
misoprostol
treatment outcome
review of literature
french abstract
misoprostol
cervical ripening
administration, buccal
administration, sublingual
---
http://www.cochrane.org/fr/CD004901/misoprostol-dans-linduction-du-travail-pour-interrompre-une-grossesse-au-deuxieme-ou-au-troisieme
2010
false
true
false
false
United Kingdom
France
abortion, induced
pregnancy
review of literature
french abstract
pregnancy trimester, second
pregnancy trimester, third
misoprostol
labor, induced
---
http://www.cochrane.org/fr/CD007207
2010
United Kingdom
France
French
french abstract
meta-analysis
pregnancy trimester, first
abortion, induced
preoperative care
mifepristone
misoprostol
abortifacient agents, nonsteroidal
cervical ripening
---
http://www.cochrane.org/fr/CD000941
2010
false
true
false
United Kingdom
France
misoprostol
treatment outcome
review of literature
french abstract
administration, intravaginal
labor onset
misoprostol
---
http://www.cochrane.org/fr/CD001338
2010
false
true
false
United Kingdom
France
treatment outcome
pregnancy
review of literature
french abstract
administration, oral
misoprostol
labor, induced
---
http://www.has-sante.fr/portail/jcms/c_666473/declenchement-artificiel-du-travail-a-partir-de-37-semaines-d-amenorrhee
http://www.has-sante.fr/portail/jcms/c_668178/declenchement-artificiel-du-travail-argumentaire
2008
true
France
French
labor, induced
france
labor, induced
labor, induced
extraembryonic membranes
oxytocics
oxytocin
dinoprostone
misoprostol
labor, induced
uterine rupture
consumer health information
practice guideline
---
http://www.has-sante.fr/portail/upload/docs/application/pdf/ct031886.pdf
http://www.has-sante.fr/portail/display.jsp?id=c_400310
2005
France
French
administration, oral
misoprostol
insurance, health, reimbursement
misoprostol
oxytocics
misoprostol
oxytocics
treatment outcome
tablets
guidelines for drug use
evaluation of the transparency committee
---