fibroblast growth factor 1

Preferred Label : fibroblast growth factor 1;

MeSH definition : A 17-kDa single-chain polypeptide growth factor that plays a significant role in the process of WOUND HEALING and is a potent inducer of PHYSIOLOGIC ANGIOGENESIS. It binds to HEPARIN, which potentiates its biological activity and protects it from proteolysis. The growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages, and also has chemotactic and mitogenic activities. It was originally named acidic fibroblast growth factor based upon its chemical properties and to distinguish it from basic fibroblast growth factor (FIBROBLAST GROWTH FACTOR 2).;

MeSH synonym : acidic fibroblast growth factor; class i heparin-binding growth factor; fgf-1; fgf1; fibroblast growth factor, acidic; hbgf-1; heparin binding growth factor, class i; heparin-binding fibroblast growth factor class i; heparin-binding growth factor, class i; fibroblast growth Factor-1;

MeSH CAS label : fibroblast growth factor (human brain acidic protein moiety reduced);

Registry Number MeSH : 104781-85-3;

MeSH annotation : DF: FGF1;

Is substance : O;

Details

Origin ID

D016220;

UMLS CUI

C0079349;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Fibroblast Growth Factor 1 [NCIt concept]
Indexing information
- S130K-HBGAM chimeric protein [MeSH Supplementary Concept]
Record concept(s)
- fibroblast growth factor 1 [MeSH concept]
Related MeSH Supplementary Concept(s)
- acidic fibroblast growth factor (1-29), Ala(16)- [MeSH Supplementary Concept]
- acidic fibroblast growth factor-Pseudomonas exotoxin A [MeSH Supplementary Concept]
- fibroblast growth factor-1 (112-147) [MeSH Supplementary Concept]
- fibroblast growth factor-1 (21-154), human [MeSH Supplementary Concept]
- fibroblast growth factor-1, S130K substituted [MeSH Supplementary Concept]
- hexafin1 peptide [MeSH Supplementary Concept]
- riferminogene pecaplasmide [MeSH Supplementary Concept]
See also inter- (CISMeF)
- Recombinant Fibroblast Growth Factor 1 [NCIt concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

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