pentostatin - CISMeF

Preferred Label : pentostatin;

MeSH definition : A potent inhibitor of ADENOSINE DEAMINASE. The drug induces APOPTOSIS of LYMPHOCYTES, and is used in the treatment of many lymphoproliferative malignancies, particularly HAIRY CELL LEUKEMIA. It is also synergistic with some other antineoplastic agents and has immunosuppressive activity.;

CISMeF synonym : wyeth brand of pentostatin; supergen brand of pentostatin; Warner-Lambert brand of pentostatin; lederle brand of pentostatin; prasfarma brand of pentostatin; deoxycoformycin;

MeSH hyponym : NSC-218321; CI-825; nipent; NSC 218321; NSC218321; CI 825; CI825;

Related MeSH term : Imidazo(4,5-d)(1,3)diazepin-8-ol, 3-(2-deoxy-beta-D-erythro-pentofuranosyl)-3,4,7,8-tetrahydro-, (R)-; 2'-Deoxycoformycin; 2' Deoxycoformycin;

MeSH CAS label : Imidazo(4,5-d)(1,3)diazepin-8-ol, 3-(2-deoxy-beta-D-erythro-pentofuranosyl)-3,4,7,8-tetrahydro-, (R)-; Imidazo(4,5-d)(1,3)diazepin-8-ol, 3-(2-deoxy-D-erythro-pentofuranosyl)-3,4,7,8-tetrahydro-, (8R)-;

MeSH Related Number : 53910-25-1 (Pentostatin);

Registry Number MeSH : 53910-25-1;

Wikipedia link : https://en.wikipedia.org/wiki/2'-Deoxycoformycin;

Is substance : O;

UNII : 395575MZO7;

InChIKey : FPVKHBSQESCIEP-JQCXWYLXSA-N;

Details

Origin ID

D015649;

UMLS CUI

C0030896;

ATC code(s)
- pentostatin [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Pentostatin [ICHI extension code]
CISMeF manual mappings
- Pentostatin poisoning (disorder) [SNOMED CT concept]
Currated CISMeF NLP mapping
- Pentostatin [ICD-11 Extension code]
- Pentostatin [NCIt concept]
- Pentostatin (substance) [SNOMED CT concept]
- pentostatin [SNOMED Notion]
False automatic mappings
- Product containing vidarabine (medicinal product) [SNOMED CT concept]
- Vidarabine [NCIt concept]
- Vidarabine (substance) [SNOMED CT concept]
- vidarabine [ATC Code]
- vidarabine [ATC Code]
- vidarabine [Substance BNPC]
- vidarabine [SNOMED Notion]
Pharmacological action(s)
- adenosine deaminase inhibitors [MeSH Descriptor]
- antineoplastic agents [MeSH Descriptor]
Record concept(s)
- CI-825 [MeSH concept]
- Co-Vidarabine [MeSH concept]
- Deoxycoformycin [MeSH concept]
- NSC-218321 [MeSH concept]
- nipent [MeSH concept]
- pentostatin [MeSH concept]
Related MeSH Supplementary Concept(s)
- 2'-deoxycoformycin 5'-phosphate [MeSH Supplementary Concept]
- 8-ketodeoxycoformycin [MeSH Supplementary Concept]
- adechlorin [MeSH Supplementary Concept]
- carbapentostain [MeSH Supplementary Concept]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
UMLS correspondences (same concept)
- Pentostatin [ICD-11 Extension code]
- Pentostatin [NCIt concept]
- Pentostatin (substance) [SNOMED CT concept]
- Product containing pentostatin (medicinal product) [SNOMED CT concept]
- pentostatin [ATC Code]
- pentostatin [SNOMED Notion]
Validated automatic mappings to BTNT
- pentostatin [ATC Code]

Keyword's position in hierarchy(ies) :

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