chloramphenicol o-acetyltransferase

Preferred Label : chloramphenicol o-acetyltransferase;

MeSH definition : An enzyme that catalyzes the acetylation of chloramphenicol to yield chloramphenicol 3-acetate. Since chloramphenicol 3-acetate does not bind to bacterial ribosomes and is not an inhibitor of peptidyltransferase, the enzyme is responsible for the naturally occurring chloramphenicol resistance in bacteria. The enzyme, for which variants are known, is found in both gram-negative and gram-positive bacteria. EC 2.3.1.28.;

MeSH synonym : chloramphenicol acetyltransferase; o-acetyltransferase, chloramphenicol; transacetylase, chloramphenicol; chloramphenicol transacetylase; cat enzyme; enzyme, cat; acetyltransferase, chloramphenicol; chloramphenicol O acetyltransferase;

MeSH CAS label : Acetyl-CoA-chloramphenicol 3-O-acetyltransferase;

MeSH Related Number : 9040-07-7 (CAS RN);

Registry Number MeSH : EC 2.3.1.28;

Wikipedia link : https://en.wikipedia.org/wiki/Chloramphenicol o-acetyltransferase;

Is substance : O;

UNII : EC 2.3.1.28;

Details

Origin ID

D015500;

UMLS CUI

C0008169;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Chloramphenicol O-acetyltransferase [NCIt concept]
Record concept(s)
- chloramphenicol O-Acetyltransferase [MeSH concept]
See also
- chloramphenicol resistance [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Chloramphenicol O-acetyltransferase [NCIt concept]
- Chloramphenicol acetyltransferase (substance) [SNOMED CT concept]
- chloramphenicol acetyltransferase [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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