Preferred Label : chloramphenicol o-acetyltransferase;

MeSH definition : An enzyme that catalyzes the acetylation of chloramphenicol to yield chloramphenicol 3-acetate. Since chloramphenicol 3-acetate does not bind to bacterial ribosomes and is not an inhibitor of peptidyltransferase, the enzyme is responsible for the naturally occurring chloramphenicol resistance in bacteria. The enzyme, for which variants are known, is found in both gram-negative and gram-positive bacteria. EC 2.3.1.28.;

MeSH synonym : chloramphenicol acetyltransferase; o-acetyltransferase, chloramphenicol; transacetylase, chloramphenicol; chloramphenicol transacetylase; cat enzyme; enzyme, cat; acetyltransferase, chloramphenicol; chloramphenicol O acetyltransferase;

MeSH CAS label : Acetyl-CoA-chloramphenicol 3-O-acetyltransferase;

MeSH Related Number : 9040-07-7 (CAS RN);

Registry Number MeSH : EC 2.3.1.28;

Wikipedia link : https://en.wikipedia.org/wiki/Chloramphenicol o-acetyltransferase;

Is substance : O;

UNII : EC 2.3.1.28;

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An enzyme that catalyzes the acetylation of chloramphenicol to yield chloramphenicol 3-acetate. Since chloramphenicol 3-acetate does not bind to bacterial ribosomes and is not an inhibitor of peptidyltransferase, the enzyme is responsible for the naturally occurring chloramphenicol resistance in bacteria. The enzyme, for which variants are known, is found in both gram-negative and gram-positive bacteria. EC 2.3.1.28.

http://www.dermis.net/dermisroot/fr/13970/diagnose.htm
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scientific and technical information
chloramphenicol o-acetyltransferase
catalase
ACT protocol

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29/07/2025


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