Preferred Label : histocompatibility antigens class i;
MeSH definition : Membrane glycoproteins consisting of an alpha subunit and a BETA 2-MICROGLOBULIN beta
subunit. In humans, highly polymorphic genes on CHROMOSOME 6 encode the alpha subunits
of class I antigens and play an important role in determining the serological specificity
of the surface antigen. Class I antigens are found on most nucleated cells and are
generally detected by their reactivity with alloantisera. These antigens are recognized
during GRAFT REJECTION and restrict cell-mediated lysis of virus-infected cells.;
MeSH synonym : class i major histocompatibility antigens; class i histocompatibility antigens; class i antigens; antigens, class i; Class I MHC Proteins; Class I Major Histocompatibility Molecules; MHC-I Molecules; MHC I Molecules; Molecules, MHC-I; MHC-I Peptides; MHC I Peptides; Peptides, MHC-I; MHC Class I Molecules; MHC-I Peptide; MHC I Peptide; Peptide, MHC-I; Class I Major Histocompatibility Antigen; MHC Class I Molecule; Class I MHC Protein; Class I Antigen; Antigen, Class I; I Antigen, Class; Class I Histocompatibility Antigen;
CISMeF synonym : i antigens, class;
MeSH hyponym : human class I antigens; Class I Human Antigens;
MeSH annotation : human & animal;
Wikipedia link : https://en.wikipedia.org/wiki/Histocompatibility antigens class i;
Is substance : O;
Origin ID : D015395;
UMLS CUI : C0019629;
Allowable qualifiers
Currated CISMeF NLP mapping
Indexing information
Record concept(s)
Related MeSH Supplementary Concept(s)
- Gogo-H [MeSH Supplementary Concept]
See also
Semantic type(s)
UMLS correspondences (same concept)
Membrane glycoproteins consisting of an alpha subunit and a BETA 2-MICROGLOBULIN beta
subunit. In humans, highly polymorphic genes on CHROMOSOME 6 encode the alpha subunits
of class I antigens and play an important role in determining the serological specificity
of the surface antigen. Class I antigens are found on most nucleated cells and are
generally detected by their reactivity with alloantisera. These antigens are recognized
during GRAFT REJECTION and restrict cell-mediated lysis of virus-infected cells.
https://www.jle.com/fr/revues/bio_rech/abc/e-docs/00/04/77/07/resume.phtml?type=text.html
https://www.jle.com/fr/revues/bio_rech/abc/e-docs/00/04/77/07/resume.phtml
2012
France
French
journal article
hemochromatosis
hemochromatosis
molecular diagnostic techniques
genetic counseling
HFE protein, human
histocompatibility antigens class i
membrane proteins
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http://www.has-sante.fr/portail/display.jsp?id=c_490567
http://www.has-sante.fr/portail/display.jsp?id=c_490566
2006
France
French
histocompatibility antigens class i
hemochromatosis
membrane proteins
mutation
hemochromatosis
assessment of professional actions
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