vinca alkaloids

Preferred Label : vinca alkaloids;

MeSH definition : A group of indole-indoline dimers which are ALKALOIDS obtained from the VINCA genus of plants. They inhibit polymerization of TUBULIN into MICROTUBULES thus blocking spindle formation and arresting cells in METAPHASE. They are some of the most useful ANTINEOPLASTIC AGENTS.;

MeSH synonym : alkaloids, vinca;

Is substance : O;

Details

Origin ID

D014748;

UMLS CUI

C0042672;

ATC code(s)
- vinca alkaloids and analogues [ATC Code]
ATC code(s)
- vinca alkaloids and analogues [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
CISMeF manual mappings
- Vinca alkaloid (substance) [SNOMED CT concept]
- Vinca alkaloid adverse reaction (disorder) [SNOMED CT concept]
- Vinca alkaloid poisoning (disorder) [SNOMED CT concept]
Currated CISMeF NLP mapping
- Vinca Alkaloid Compound [NCIt concept]
- vinca alkaloid [SNOMED Notion]
Indexing information
- minovine [MeSH Supplementary Concept]
Pharmacological action(s)
- tubulin modulators [MeSH Descriptor]
Record concept(s)
- vinca alkaloids [MeSH concept]
Related MeSH Supplementary Concept(s)
- 11-methyl-20,21-dinoreburnamenine [MeSH Supplementary Concept]
- 16a'-homo-leurosidine [MeSH Supplementary Concept]
- 2'-hydroxyethyl apovincaminate [MeSH Supplementary Concept]
- 2-(nitrooxy)ethyl apovincaminate [MeSH Supplementary Concept]
- 21'-oxoleurosine [MeSH Supplementary Concept]
- 6-hydroxyvinburnine [MeSH Supplementary Concept]
- AF 698 [MeSH Supplementary Concept]
- EC 0489 [MeSH Supplementary Concept]
- EC140 compound [MeSH Supplementary Concept]
- EC145 [MeSH Supplementary Concept]
- LHT 2 - 02 [MeSH Supplementary Concept]
- RGH 4417 [MeSH Supplementary Concept]
- S 12363 [MeSH Supplementary Concept]
- VA 033 [MeSH Supplementary Concept]
- apovincaminic acid [MeSH Supplementary Concept]
- catharanthine [MeSH Supplementary Concept]
- catharanthinol [MeSH Supplementary Concept]
- conophylline [MeSH Supplementary Concept]
- dihydrodinoreburnameninol [MeSH Supplementary Concept]
- eburnamonine [MeSH Supplementary Concept]
- ent-4-desacetoxy-6,7-dihydrovindorosine [MeSH Supplementary Concept]
- ethyl 21,21,21-trifluoroapovincaminate [MeSH Supplementary Concept]
- formyl-leurosine [MeSH Supplementary Concept]
- herbadine [MeSH Supplementary Concept]
- hunterioside [MeSH Supplementary Concept]
- leurosidine N'b-oxide [MeSH Supplementary Concept]
- leurosine [MeSH Supplementary Concept]
- leurosine methiodide [MeSH Supplementary Concept]
- majdine [MeSH Supplementary Concept]
- methoxymethyl apovincaminate [MeSH Supplementary Concept]
- piracetam, vinpocetine drug combination [MeSH Supplementary Concept]
- pleurosine [MeSH Supplementary Concept]
- quebrachidine [MeSH Supplementary Concept]
- roseadine [MeSH Supplementary Concept]
- rutovincine [MeSH Supplementary Concept]
- strictosamide [MeSH Supplementary Concept]
- strictosidine [MeSH Supplementary Concept]
- vincarubine [MeSH Supplementary Concept]
- vinconate [MeSH Supplementary Concept]
- vincorine [MeSH Supplementary Concept]
- vindolicine [MeSH Supplementary Concept]
- vinpocetine [MeSH Supplementary Concept]
- vinzolidine [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Vinca Alkaloid Compound [NCIt concept]
- Vinca alkaloid (substance) [SNOMED CT concept]
- vinca alkaloid [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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