SRS-A - CISMeF

Preferred Label : SRS-A;

MeSH definition : A group of LEUKOTRIENES; (LTC4; LTD4; and LTE4) that is the major mediator of BRONCHOCONSTRICTION; HYPERSENSITIVITY; and other allergic reactions. Earlier studies described a slow-reacting substance of ANAPHYLAXIS released from lung by cobra venom or after anaphylactic shock. The relationship between SRS-A leukotrienes was established by UV which showed the presence of the conjugated triene. (From Merck Index, 11th ed);

MeSH synonym : slow reacting substance of anaphylaxis;

MeSH annotation : /biosyn /physiol permitted;

Wikipedia link : https://en.wikipedia.org/wiki/Slow reacting substance of anaphylaxis;

Is substance : O;

Details

Origin ID

D013189;

UMLS CUI

C0038091;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Clinical Trial Final Statistical Report Documentation [NCIt concept]
- Gamma-Synuclein [NCIt concept]
- MSR1 wt Allele [NCIt concept]
- SCTR wt Allele [NCIt concept]
- SNCG wt Allele [NCIt concept]
- Senior [NCIt concept]
- Skin Response Domain [NCIt concept]
- Slow reacting substance-A of anaphylaxis (substance) [SNOMED CT concept]
- Somatostatin Receptor Scintigraphy [NCIt concept]
- Strontium [NCIt concept]
- Suriname [NCIt concept]
- Sustained Release Dosage Form [NCIt concept]
- slow reacting substance-a of anaphylaxis [SNOMED Notion]
Record concept(s)
- SRS-A [MeSH concept]
Related MeSH Supplementary Concept(s)
- 16-carboxy-17,18,19,20-tetranor-14,15-dihydro-N-acetylleukotriene E4 [MeSH Supplementary Concept]
- 16-carboxytetranordihyroleukotriene E4 [MeSH Supplementary Concept]
- 18-carboxy-19,20-dinor-N-acetylleukotriene E4 [MeSH Supplementary Concept]
- 2-norleukotriene D1 [MeSH Supplementary Concept]
- 20,20,20-trifluoroleukotriene E4 [MeSH Supplementary Concept]
- 4-hydroxy-5-((2-carboxyethyl)thio)-6-nonadecenoic acid [MeSH Supplementary Concept]
- 5-hydroxy-6-mercapto-7,9,11,14-eicosatetraenoic acid [MeSH Supplementary Concept]
- 9,10,11,12,14,15-hexahydroleukotriene C4 [MeSH Supplementary Concept]
- BAY u9773 [MeSH Supplementary Concept]
- CGP 34064A [MeSH Supplementary Concept]
- N-acetylleukotriene D4 [MeSH Supplementary Concept]
- leukotriene C-2 [MeSH Supplementary Concept]
- leukotriene C-3 [MeSH Supplementary Concept]
- leukotriene C-4 sulfone [MeSH Supplementary Concept]
- leukotriene C-5 [MeSH Supplementary Concept]
- leukotriene D-3 [MeSH Supplementary Concept]
- leukotriene D-4 sulfone [MeSH Supplementary Concept]
- leukotriene E-4 sulfone [MeSH Supplementary Concept]
- leukotriene F-4 [MeSH Supplementary Concept]
- leukotriene F-4 sulfone [MeSH Supplementary Concept]
See also
- anaphylaxis [MeSH Descriptor]
Semantic type(s)
- Biologically Active Substance [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Slow reacting substance-A of anaphylaxis (substance) [SNOMED CT concept]
- slow reacting substance-a of anaphylaxis [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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