" /> farnesyl-diphosphate farnesyltransferase - CISMeF





Preferred Label : farnesyl-diphosphate farnesyltransferase;

MeSH definition : The first committed enzyme of the biosynthesis pathway that leads to the production of STEROLS. it catalyzes the synthesis of SQUALENE from farnesyl pyrophosphate via the intermediate PRESQUALENE PYROPHOSPHATE. This enzyme is also a critical branch point enzyme in the biosynthesis of ISOPRENOIDS that is thought to regulate the flux of isoprene intermediates through the sterol pathway.;

MeSH synonym : fpp-fpp farnesyl transferase; farnesyl transferase, fpp-fpp; transferase, fpp-fpp farnesyl; synthase, squalene; synthetase, squalene; farnesyldiphosphate-farnesyldiphosphate farnesyltransferase; presqualene-diphosphate synthase; presqualene diphosphate synthase; farnesyldiphosphate farnesyldiphosphate farnesyltransferase; farnesyltransferase, farnesyl-diphosphate; farnesyltransferase, farnesyldiphosphate-farnesyldiphosphate; fpp fpp farnesyl transferase; squalene synthase; squalene synthetase; synthase, presqualene-diphosphate; farnesyl diphosphate farnesyltransferase;

Registry Number MeSH : EC 2.5.1.21;

Wikipedia link : https://en.wikipedia.org/wiki/Farnesyl-diphosphate farnesyltransferase;

Is substance : O;

UNII : EC 2.5.1.21;

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The first committed enzyme of the biosynthesis pathway that leads to the production of STEROLS. it catalyzes the synthesis of SQUALENE from farnesyl pyrophosphate via the intermediate PRESQUALENE PYROPHOSPHATE. This enzyme is also a critical branch point enzyme in the biosynthesis of ISOPRENOIDS that is thought to regulate the flux of isoprene intermediates through the sterol pathway.

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27/07/2025


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