1-((1-(3-acetoxy-2,2-dimethylpropyl)-7-chloro-5-(2,3-dimethoxyphenyl)-2-oxo-1,2,3,5-tetrahydro-4,1-benzoxazepin-3-yl)acetyl)piperidine-4-acetic acid

Preferred Label : 1-((1-(3-acetoxy-2,2-dimethylpropyl)-7-chloro-5-(2,3-dimethoxyphenyl)-2-oxo-1,2,3,5-tetrahydro-4,1-benzoxazepin-3-yl)acetyl)piperidine-4-acetic acid;

MeSH note : inhibits squalene synthase; structure in first source;

CISMeF synonym : TAK 475;

MeSH synonym : (1-(2-(1-(2-carboxyoxy-1,1-dimethylethyl)-7-chloro-5-(2,3-dimethoxyphenyl)-2-oxo-1,2,3,5-tetrahydrobenzo(e)(1,4)oxazepin-3-yl)acetyl)piperidin-4-yl)acetic acid; lapaquistat;

MeSH hyponym : TAK475; TAK-475;

Is substance : O;

Details

Origin ID

C466644;

UMLS CUI

C1144136;

Automatic exact mappings (from CISMeF team)
- Lapaquistat [NCIt concept]
MeSH indexing information
- farnesyl-diphosphate farnesyltransferase [MeSH Descriptor]
MeSH term(s) associated for indexing
- oxazepines [MeSH Descriptor]
- piperidines [MeSH Descriptor]
Record concept(s)
- 1-((1-(3-acetoxy-2,2-dimethylpropyl)-7-chloro-5-(2,3-dimethoxyphenyl)-2-oxo-1,2,3,5-tetrahydro-4,1-benzoxazepin-3-yl)acetyl)piperidine-4-acetic acid [MeSH concept]
- TAK 475 [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Lapaquistat [NCIt concept]

Keyword's position in hierarchy(ies) :

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