squalestatin 1

Preferred Label : squalestatin 1;

MeSH note : structure given in first source; inhibits both mammalian and fungal squalene synthetase; from fungus Phoma sp (Coelomycetes);

CISMeF synonym : 7-deoxy zaragozic acid;

MeSH synonym : zaragozic acid A; squalestatin; squalestatin s1;

MeSH CAS label : L-erythro-L-glycero-D-altro-7-trideculo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-c-carboxy-8,9,10,12,13-pentadeoxy-10-methylene-12-(phenylmethyl)-, 11-acetate 5-((2E,4S,6S)-4,6-dimethyl-2-octenoate), (7S)-;

MeSH Related Number : 142561-96-4;

Registry Number MeSH : 142561-96-4;

Is substance : O;

UNII : 1117HVX02L;

Details

Origin ID

C075117;

UMLS CUI

C0169226;

MeSH indexing information
- farnesyl-diphosphate farnesyltransferase [MeSH Descriptor]
MeSH term(s) associated for indexing
- Bridged Bicyclo Compounds, Heterocyclic [MeSH Descriptor]
- tricarboxylic acids [MeSH Descriptor]
Pharmacological action(s)
- anticholesteremic agents [MeSH Descriptor]
- antifungal agents [MeSH Descriptor]
- enzyme inhibitors [MeSH Descriptor]
Record concept(s)
- 7-deoxy zaragozic acid [MeSH concept]
- squalestatin 1 [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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