serotonin - CISMeF

Preferred Label : serotonin;

MeSH definition : A biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. Serotonin mediates several important physiological functions including neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity. Multiple receptor families (RECEPTORS, SEROTONIN) explain the broad physiological actions and distribution of this biochemical mediator.;

MeSH synonym : 5-hydroxytryptamine; 3-(2-aminoethyl)-1h-indol-5-ol; 5-ht; enteramine; hippophaine; 5 hydroxytryptamine;

CISMeF synonym : 3-(2-aminoethyl)indol-5-ol;

Related MeSH term : hydroxytryptamine;

MeSH CAS label : 1H-Indol-5-ol, 3-(2-aminoethyl)-;

MeSH Related Number : 50-67-9 (Serotonin);

Registry Number MeSH : 50-67-9;

MeSH annotation : /antag SEROTONIN ANTAGONISTS but consider also SEROTONIN UPTAKE INHIBITORS; /antag SEROTONIN ANTAGONISTS but consider also SELECTIVE SEROTONIN REUPTAKE INHIBITORS;

Wikipedia link : https://en.wikipedia.org/wiki/Serotonin;

Codes EINECS : 200-058-9;

Is substance : O;

UNII : 333DO1RDJY;

InChIKey : QZAYGJVTTNCVMB-UHFFFAOYSA-N;

Details

Origin ID

D012701;

UMLS CUI

C0036751;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Serotonin [ICHI extension code]
- Serotonin Measurement [NCIt concept]
- serotonin [medical devices type]
- serotonine [EMDN type]
CISMeF manual mappings
- 3-(2-aminoethyl)indol-5-ol [Substance BNPC]
Currated CISMeF NLP mapping
- Serotonin [ICD-11 Extension code]
- Serotonin [NCIt concept]
- Serotonin [FMA entity]
- Serotonin [LOINC component]
- Serotonin (substance) [SNOMED CT concept]
- serotonin [SNOMED Notion]
Indexing information
- serotonin-binding protein [MeSH Supplementary Concept]
Pharmacological action(s)
- serotonin receptor agonists [MeSH Descriptor]
Record concept(s)
- hydroxytryptamine [MeSH concept]
- serotonin [MeSH concept]
Related MeSH Supplementary Concept(s)
- (4-serotonyl)-4-serotonin [MeSH Supplementary Concept]
- 1-oxo-5-hydroxytryptamine [MeSH Supplementary Concept]
- 111In-bis-5-hydroxytryptamide-diethylenetriamine-pentaacetate [MeSH Supplementary Concept]
- 2-methyl-5-HT [MeSH Supplementary Concept]
- 3-(2-(4-azidobenzamidino)ethyl)-5-hydroxyindole [MeSH Supplementary Concept]
- 4,4'-bis(N-feruloyl)serotonin [MeSH Supplementary Concept]
- 4,6-difluoroserotonin [MeSH Supplementary Concept]
- 4-(7'-(tryptamine-4,5-dione))-2,4''-bis-5-hydroxytryptamine [MeSH Supplementary Concept]
- 4-azido-3-nitrophenyl-azo-(5-hydroxytryptamine) [MeSH Supplementary Concept]
- 4-nitro-5-HT [MeSH Supplementary Concept]
- 4-nitroso-5-HT [MeSH Supplementary Concept]
- 5-benzyloxytryptamine [MeSH Supplementary Concept]
- 5-carboxamidotryptamine [MeSH Supplementary Concept]
- 5-hydroxy-N,N-diisopropyltryptamine [MeSH Supplementary Concept]
- 5-hydroxytryptamine O-sulfate [MeSH Supplementary Concept]
- 5-hydroxytryptamine-tetramethylrhodamine [MeSH Supplementary Concept]
- 5-methoxy-alpha-methyltryptamine [MeSH Supplementary Concept]
- 5-sulfatoxy-N-acetylserotonin [MeSH Supplementary Concept]
- 6-fluoroserotonin [MeSH Supplementary Concept]
- 6-hydroxytryptamine [MeSH Supplementary Concept]
- 7,7'-bis-(5-hydroxytryptamine-4-one) [MeSH Supplementary Concept]
- 7-azaserotonin [MeSH Supplementary Concept]
- N,N-di-n-propylserotonin [MeSH Supplementary Concept]
- N-(2-nitro-4-azidophenyl)serotonin [MeSH Supplementary Concept]
- N-(4-azido-2-nitrophenyl)-5-hydroxytryptamine [MeSH Supplementary Concept]
- N-(p-coumaroyl)serotonin [MeSH Supplementary Concept]
- N-acetylserotonin [MeSH Supplementary Concept]
- N-caffeoylserotonin [MeSH Supplementary Concept]
- N-feruloylserotonin [MeSH Supplementary Concept]
- N-methylserotonin [MeSH Supplementary Concept]
- alpha-methylserotonin [MeSH Supplementary Concept]
- arachidonoylserotonin [MeSH Supplementary Concept]
- arachidonyl serotonin [MeSH Supplementary Concept]
- beta-hydroxyserotonin [MeSH Supplementary Concept]
- bufopyramide [MeSH Supplementary Concept]
- creatinine sulfate, serotonin drug combination [MeSH Supplementary Concept]
- desoxyfructo-serotonin [MeSH Supplementary Concept]
- desoxyribulo-serotonin [MeSH Supplementary Concept]
- eicosanoyl-5-hydroxytryptamide [MeSH Supplementary Concept]
- gamma-glutamyl-5-hydroxytryptamine [MeSH Supplementary Concept]
- nb-(alpha-hydroxynaphthoyl)serotonin [MeSH Supplementary Concept]
- omega-N-methyl-4-hydroxytryptamine [MeSH Supplementary Concept]
- serotonin adipinate [MeSH Supplementary Concept]
- serotonin-BSA conjugate [MeSH Supplementary Concept]
- serotonin-O-carboxymethyl-Gly-Tyr [MeSH Supplementary Concept]
- serotonin-rat serum albumin conjugate [MeSH Supplementary Concept]
Related MeSH term(s)
- serotonin antagonists [MeSH Descriptor]
- serotonin receptor agonists [MeSH Descriptor]
See also
- receptors, serotonin [MeSH Descriptor]
- serotonin agents [MeSH Descriptor]
- serotonin syndrome [MeSH Descriptor]
Semantic type(s)
- Biologically Active Substance [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- 3-(2-aminoethyl)indol-5-ol [Substance BNPC]
- Serotonin [ICD-11 Extension code]
- Serotonin [FMA entity]
- Serotonin [NCIt concept]
- Serotonin [LOINC component]
- Serotonin (substance) [SNOMED CT concept]
- serotonin [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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