Preferred Label : reserpine;
MeSH definition : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine
inhibits the uptake of norepinephrine into storage vesicles resulting in depletion
of catecholamines and serotonin from central and peripheral axon terminals. It has
been used as an antihypertensive and an antipsychotic as well as a research tool,
but its adverse effects limit its clinical use.;
CISMeF synonym : vangarde brand of reserpine; vitarine brand of reserpine;
MeSH hyponym : raupasil; rausedil; serpasil; V-Serp; raunervil; serpivite; Rausedyl; V Serp;
MeSH CAS label : Yohimban-16-carboxylic acid, 11,17-dimethoxy-18-((3,4,5-trimethoxybenzoyl)oxy)-, methyl
ester, (3beta,16beta,17alpha,18beta,20alpha)-;
MeSH Related Number : 50-55-5 (Reserpine);
Registry Number MeSH : 50-55-5;
MeSH annotation : reserpine derivatives RESERPINE /analogs;
Wikipedia link : https://en.wikipedia.org/wiki/Reserpine;
Codes EINECS : 200-047-9;
Is substance : O;
UNII : 8B1QWR724A;
InChIKey : QEVHRUUCFGRFIF-MDEJGZGSSA-N;
Origin ID : D012110;
UMLS CUI : C0035179;
ATC code(s)
Allowable qualifiers
Automatic exact mappings (from CISMeF team)
CISMeF manual mappings
Currated CISMeF NLP mapping
Pharmacological action(s)
Record concept(s)
Related MeSH Supplementary Concept(s)
- CD 3400 [MeSH Supplementary Concept]
- hyparez [MeSH Supplementary Concept]
See also inter- (CISMeF)
Semantic type(s)
UMLS correspondences (same concept)
Validated automatic mappings to BTNT
An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine
inhibits the uptake of norepinephrine into storage vesicles resulting in depletion
of catecholamines and serotonin from central and peripheral axon terminals. It has
been used as an antihypertensive and an antipsychotic as well as a research tool,
but its adverse effects limit its clinical use.
http://www.has-sante.fr/portail/jcms/c_1730849/fr/tensionorme
http://www.has-sante.fr/portail/jcms/c_663799/tensionorme
2014
false
France
French
drug combinations
administration, oral
reserpine and diuretics
bendroflumethiazide
antihypertensive agents
diuretics
sodium chloride symporter inhibitors
reserpine
insurance, health, reimbursement
hypertension
evaluation of the transparency committee
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http://www.cochrane.org/fr/CD007655
2009
United Kingdom
France
French
meta-analysis
hypertension
reserpine
treatment outcome
antihypertensive agents
french abstract
---