complement factor B

Preferred Label : complement factor B;

MeSH definition : A glycine-rich, heat-labile serum glycoprotein that contains a component of the C3 CONVERTASE ALTERNATE PATHWAY (C3bBb). Bb, a serine protease, is generated when factor B is cleaved by COMPLEMENT FACTOR D into Ba and Bb.;

MeSH synonym : factor b, complement; proactivator, complement 3; complement factor b, alternative pathway; factor b, properdin; complement protein factor b; proactivator, c3; complement protein b; c3 proactivator; protein b, complement; factor b; complement 3 proactivator; properdin factor b; c3pa;

MeSH hyponym : complement factor bb; properdin factor bf F1; complement factor ba; properdin factor bf; Bb, Complement Factor; Factor Bb, Complement; Properdin Factor Bb; Factor Bb, Properdin; Complement Factor B-Derived Fragment Bb; Complement Factor B Derived Fragment Bb; Bb Fragment of Factor B; Complement Factor B Fragment, Bb; Factor Bf, Properdin; Factor Ba, Complement; Properdin Factor Ba; Factor Ba, Properdin;

MeSH Related Number : complement factor bb; EC 3.4.21.47;

Registry Number MeSH : EC 3.4.21.47;

Related CAS MeSH : EC 3.4.21.47 (Complement factor bb);

Is substance : O;

UNII : EC 3.4.21.47;

Details

Origin ID

D011415;

UMLS CUI

C0033453;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Complement Bb Measurement [NCIt concept]
- Complement C3 [LOINC component]
- Complement Factor B [NCIt concept]
- Complement factor [MedDRA Preferred Term]
- Complement factor (substance) [SNOMED CT concept]
- Complement factor BA measurement (procedure) [SNOMED CT concept]
- Complement factor BB measurement (procedure) [SNOMED CT concept]
- Complement factor Ba [LOINC component]
- Complement factor Ba (substance) [SNOMED CT concept]
- Complement factor Bb [LOINC component]
- Complement factor Bb (substance) [SNOMED CT concept]
- Complement factor C3 [MedDRA Preferred Term]
- Complement factor b [OMIM gene]
- Complement factor increased [MedDRA Preferred Term]
- Factor [NCIt concept]
- Factor B (substance) [SNOMED CT concept]
- Mathematical Factor [NCIt concept]
- blood-coagulation factor ii [Substance BNPC]
- blood-coagulation factor iii [Substance BNPC]
- blood-coagulation factor v [Substance BNPC]
- blood-coagulation factor x [Substance BNPC]
- complement factor B [HGNC gene]
- complement factor b, nos [SNOMED Notion]
- complement factor ba [SNOMED Notion]
- complement factor bb [SNOMED Notion]
- complement factor d [SNOMED Notion]
- f factor [SNOMED Notion]
- factor [IUPAC Term]
- factor h [SNOMED Notion]
- fibrinogens [Substance BNPC]
- obsolete alternative-complement-pathway C3/C5 convertase activity [GO term]
- r factor [SNOMED Notion]
Currated CISMeF NLP mapping
- Complement factor B [LOINC component]
- Complement factor b [OMIM Phenotype]
- complement factor B [ORDO Gene]
Pharmacological action(s)
- immunologic factors [MeSH Descriptor]
Record concept(s)
- complement factor B [MeSH concept]
- complement factor ba [MeSH concept]
- complement factor bb [MeSH concept]
- properdin factor bf [MeSH concept]
- properdin factor bf F1 [MeSH concept]
Related MeSH Supplementary Concept(s)
- complement C3bBa complex [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- Complement factor B [LOINC component]
- Factor B (substance) [SNOMED CT concept]
- complement factor b, nos [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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