pro-opiomelanocortin

Preferred Label : pro-opiomelanocortin;

MeSH definition : A 30-kDa protein synthesized primarily in the ANTERIOR PITUITARY GLAND and the HYPOTHALAMUS. It is also found in the skin and other peripheral tissues. Depending on species and tissues, POMC is cleaved by PROHORMONE CONVERTASES yielding various active peptides including ACTH; BETA-LIPOTROPIN; ENDORPHINS; MELANOCYTE-STIMULATING HORMONES; and others (GAMMA-LPH; CORTICOTROPIN-LIKE INTERMEDIATE LOBE PEPTIDE; N-terminal peptide of POMC or NPP).;

MeSH synonym : proopiocortin; pro-opio-melanocortin; acth beta lipotropin precursor; proopiomelanocortin; endorphin acth precursor; pro acth endorphin; acth-beta-lipotropin precursor; acth-endorphin precursor; pro-opiocortin; pro opiocortin; pomc; pro opio melanocortin; endorphin-acth precursor; acth endorphin precursor; corticotropin-beta-lipotropin precursor; corticotropin beta lipotropin precursor; pro-acth-endorphin; pro opiomelanocortin;

MeSH hyponym : opiocortin; preproopiomelanocortin; Pre-POMC; Pre POMC; Pre-pro-opiocortin; Pre pro opiocortin;

MeSH CAS label : opiomelanocortin, pro-;

MeSH Related Number : preproopiomelanocortin; opiocortin; 76775-14-9; 78321-08-1;

Registry Number MeSH : 66796-54-1;

Related CAS MeSH : 76775-14-9 (Preproopiomelanocortin); 78321-08-1 (Opiocortin);

Wikipedia link : https://en.wikipedia.org/wiki/Proopiomelanocortin;

Is substance : O;

Details

Origin ID

D011333;

UMLS CUI

C0033195;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Pro-Opiomelanocortin [NCIt concept]
- Pro-opiomelanocortin (substance) [SNOMED CT concept]
- pro-opiomelanocortin [SNOMED Notion]
Record concept(s)
- Pro-Opiomelanocortin [MeSH concept]
- opiocortin [MeSH concept]
- preproopiomelanocortin [MeSH concept]
Related MeSH Supplementary Concept(s)
- MSH, Lys-gamma(2) [MeSH Supplementary Concept]
- MSH, Lys-gamma(3) [MeSH Supplementary Concept]
- N-POMC (1-28) [MeSH Supplementary Concept]
- joining peptide, pro-opiomelanocortin [MeSH Supplementary Concept]
- pomca protein, zebrafish [MeSH Supplementary Concept]
- pro-opiomelanocortin (1-49) [MeSH Supplementary Concept]
- pro-opiomelanocortin (1-77) [MeSH Supplementary Concept]
- pro-opiomelanocortin amino-terminal glycopeptide [MeSH Supplementary Concept]
- pro-opiomelanocortin human joining peptide(77-109) [MeSH Supplementary Concept]
- pro-opiomelanocortin joining peptide(14-23) [MeSH Supplementary Concept]
- pro-opiomelanocortin joining peptide(77-97) [MeSH Supplementary Concept]
- pro-opiomelanocortin joining peptide(79-108) [MeSH Supplementary Concept]
- proopiocortin fragments [MeSH Supplementary Concept]
- proopiomelanocortin deficiency [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Hormone [UMLS semantic type]
UMLS correspondences (same concept)
- Pro-opiomelanocortin (substance) [SNOMED CT concept]
- pro-opiomelanocortin [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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