Preferred Label : podophyllotoxin;
MeSH definition : A lignan (LIGNANS) found in PODOPHYLLIN resin from the roots of PODOPHYLLUM plants.
It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic.
It is very irritating to skin and mucous membranes, has keratolytic actions, has been
used to treat warts and keratoses, and may have antineoplastic properties, as do some
of its congeners and derivatives.;
MeSH synonym : podofilox;
CISMeF synonym : ardern brand of podophyllotoxin; canderm brand of podophyllotoxin; fides ecopharma brand of podophyllotoxin; hamilton brand of podophyllotoxin; newport brand of podophyllotoxin; oclassen brand of podophyllotoxin; paddock brand of podophyllotoxin; paladin brand of podophyllotoxin; stiefel brand of podophyllotoxin; wolff brand of podophyllotoxin; yamanouchi brand of podophyllotoxin;
MeSH hyponym : podophyllotoxin, (5R-(5 alpha,5a alpha,8a alpha,9 alpha))-Isomer; podophyllotoxin, (5R-(5 alpha,5a alpha,8a alpha,9 beta))-Isomer; condyline; wartec; podophyllotoxin, (5R-(5 alpha,5a beta,8a alpha,9 beta))-Isomer; podophyllotoxin, (5R-(5 alpha,5a alpha,8a beta,9 alpha))-Isomer; Podocon-25; condylox; Warticon; Podofilm;
Related MeSH term : CPH86; epipodophyllotoxin;
MeSH CAS label : Furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-,
(5R-(5alpha,5abeta,8aalpha,9alpha))-;
MeSH Related Number : podophyllotoxin, (5R-(5 alpha,5a alpha,8a alpha,9 beta))-Isomer; podophyllotoxin, (5R-(5 alpha,5a alpha,8a beta,9 alpha))-Isomer; podophyllotoxin, (5R-(5 alpha,5a beta,8a alpha,9 beta))-Isomer; podophyllotoxin, (5R-(5 alpha,5a alpha,8a alpha,9 alpha))-Isomer; 4375-06-8 ((5R-(5 alpha,5a alpha,8a alpha,9 beta))-isomer); 4375-07-9 ((5R-(5 alpha,5a beta,8a alpha,9 beta))-isomer); 477-47-4 ((5R-(5 alpha,5a alpha,8a alpha,9 alpha))-isomer); 518-28-5 (Podophyllotoxin); 55568-79-1 ((5R-(5 alpha,5a alpha,8a beta,9 alpha))-isomer);
Registry Number MeSH : 518-28-5;
Related CAS MeSH : 4375-06-8 (Podophyllotoxin, (5R-(5 alpha,5a alpha,8a alpha,9 beta))-Isomer); 55568-79-1 (Podophyllotoxin, (5R-(5 alpha,5a alpha,8a beta,9 alpha))-Isomer); 4375-07-9 (Podophyllotoxin, (5R-(5 alpha,5a beta,8a alpha,9 beta))-Isomer); 477-47-4 (Podophyllotoxin, (5R-(5 alpha,5a alpha,8a alpha,9 alpha))-Isomer);
MeSH annotation : /biosyn permitted if by plant;
Wikipedia link : https://en.wikipedia.org/wiki/Podophyllotoxin;
Is substance : O;
UNII : L36H50F353;
InChIKey : YJGVMLPVUAXIQN-XVVDYKMHSA-N;
Origin ID : D011034;
UMLS CUI : C0032334;
ATC code(s)
ATC code(s)
Allowable qualifiers
Automatic exact mappings (from CISMeF team)
CISMeF manual mappings
Currated CISMeF NLP mapping
False automatic mappings
Pharmacological action(s)
Record concept(s)
Related MeSH Supplementary Concept(s)
- CIP-36 [MeSH Supplementary Concept]
- F14512 [MeSH Supplementary Concept]
- GP 11 [MeSH Supplementary Concept]
- GP 7 [MeSH Supplementary Concept]
- NK 611 [MeSH Supplementary Concept]
Semantic type(s)
UMLS correspondences (same concept)
Validated automatic mappings to BTNT
A lignan (LIGNANS) found in PODOPHYLLIN resin from the roots of PODOPHYLLUM plants.
It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic.
It is very irritating to skin and mucous membranes, has keratolytic actions, has been
used to treat warts and keratoses, and may have antineoplastic properties, as do some
of its congeners and derivatives.
https://www.has-sante.fr/portail/jcms/c_2879354/fr/condyline
2018
false
true
false
France
podophyllotoxin
insurance, health, reimbursement
treatment outcome
condylomata acuminata
podophyllotoxin
evaluation of the transparency committee
---
http://www.has-sante.fr/portail/jcms/c_1725320/fr/condyline
http://www.has-sante.fr/portail/jcms/c_724400/condyline
2014
false
false
false
France
French
evaluation of the transparency committee
insurance, health, reimbursement
podophyllotoxin
podophyllotoxin
administration, topical
keratolytic agents
condylomata acuminata
treatment outcome
---
http://www.lecrat.eu/?s=Podophyllotoxine
2013
France
French
pregnancy
condylomata acuminata
podophyllotoxin
keratolytic agents
podophyllotoxin
drug information
---
https://www.therapeutique-dermatologique.org/spip.php?article1385
2008
France
scientific and technical information
podophyllotoxin
---